Department of Cardiology, Istanbul University Institute of Cardiology, Istanbul, Turkey.
Angiology. 2012 Jul;63(5):325-9. doi: 10.1177/0003319711418957. Epub 2011 Aug 25.
We evaluated the relationship between admission blood glucose levels and estimated coronary flow by the thrombolysis in myocardial infarction (TIMI) frame count (TFC) method in patients with ST-segment elevation myocardial infarction (STEMI) undergoing primary percutaneous coronary intervention (pPCI). The TFC of 121 consecutive patients with STEMI were evaluated after pPCI. Patients with admission glucose levels > 198 mg/dL (11 mmol/L) were defined as hyperglycemic. Hyperglycemia was observed in 36 (29.8%) patients. The TFC was significantly higher in patients with hyperglycemia (70.75 [10-96] vs 56.87 [8-100], P = .04). No-reflow frequency was higher in the hyperglycemia group (44.4% vs 23.5%, P = .02). In multivariate linear regression analysis admission glucose was an independent predictor of high TFC (B = 0.21, P = .02). Our findings suggest that admission blood glucose is a predictor of TFC which reflects coronary blood flow.
我们评估了入院血糖水平与接受直接经皮冠状动脉介入治疗（pPCI）的 ST 段抬高型心肌梗死（STEMI）患者的心肌梗死溶栓治疗（TIMI）帧数计数（TFC）法估计的冠状动脉血流之间的关系。对 121 例连续 STEMI 患者 pPCI 后的 TFC 进行了评估。入院时血糖水平＞198mg/dL（11mmol/L）的患者被定义为高血糖。高血糖患者 36 例（29.8%）。高血糖患者的 TFC 明显较高（70.75[10-96] vs 56.87[8-100]，P =.04）。无复流发生率在高血糖组较高（44.4% vs 23.5%，P =.02）。多元线性回归分析显示，入院血糖是 TFC 升高的独立预测因子（B = 0.21，P =.02）。我们的研究结果表明，入院血糖是 TFC 的预测因子，TFC 反映了冠状动脉血流。
