Diabetes, Endocrinology, and Obesity Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland, USA.
Diabetes Care. 2011 Oct;34(10):2297-9. doi: 10.2337/dc11-1055. Epub 2011 Aug 26.
Metabolic risk and metabolic syndrome (MetSyn) prevalence were compared in Africans who immigrated to the U.S. and African Americans. If MetSyn were an effective predictor of cardiometabolic risk, then the group with a worse metabolic risk profile would have a higher rate of MetSyn.
Cross-sectional analyses were performed on 95 men (39 Africans, 56 African Americans, age 38 ± 6 years [mean ± SD]). Glucose tolerance was determined by oral glucose tolerance test, visceral adipose tissue (VAT) was determined by computerized tomography, and MetSyn was determined by the presence of three of five factors: central obesity, hypertriglyceridemia, low levels of HDL cholesterol, hypertension, and fasting hyperglycemia.
MetSyn prevalence was similar in Africans and African Americans (10 vs. 13%, P = 0.74), but hypertension, glycemia (fasting and 2-h glucose), and VAT were higher in Africans.
African immigrants have a worse metabolic profile than African Americans but a similar prevalence of MetSyn. Therefore, MetSyn may underpredict metabolic risk in Africans.
比较移居美国的非洲人和非裔美国人的代谢风险和代谢综合征（MetSyn）患病率。如果代谢综合征是心血管代谢风险的有效预测指标，那么代谢风险状况较差的人群代谢综合征的发病率应该更高。
对 95 名男性（39 名非洲人，56 名非裔美国人，年龄 38 ± 6 岁）进行了横断面分析。通过口服葡萄糖耐量试验确定葡萄糖耐量，通过计算机断层扫描确定内脏脂肪组织（VAT），通过存在五个因素中的三个来确定代谢综合征：中心性肥胖、高三酰甘油血症、低水平高密度脂蛋白胆固醇、高血压和空腹高血糖。
非洲人和非裔美国人的代谢综合征患病率相似（10%比 13%，P = 0.74），但非洲人高血压、血糖（空腹和 2 小时血糖）和 VAT 更高。
非洲移民的代谢状况比非裔美国人差，但代谢综合征的患病率相似。因此，代谢综合征可能会低估非洲人的代谢风险。
