Mikamoto Masaaki, Seo Yoshinobu, Ito Tamio, Nakagawara Jyoji, Nakamura Hirohiko, Tanaka Shinya
Department of Neurosurgery, Nakamura Memorial Hospital, Cho-ku, Sapporo-city, Hokkaido, Japan.
No Shinkei Geka. 2011 Sep;39(9):859-64.
Meningeal melanocytomas are uncommon intracranial tumors and extremely rare in the cerebellopontine angle (CPA). The tumors are generally considered to be benign because they lack malignant features in histological examination, but several literatures describe malignant behavior of the tumors such as high frequency of local recurrence, malignant transformation with leptomeningeal seeding. We describe a case of meningeal melanocytoma in the CPA and discuss the features of the tumor. The case was a 43-year-old woman with a right CPA exta-axial mass suffering from vertigo and nausea. Computed tomography (CT) and magnetic resonance imaging (MRI) showed a mass in the right CPA. The mass was hyperintense on T1-weighted images and hypointense on T2-weighted images. Surgical removal was done and pathological diagnosis was made as meningeal melanocytoma. Twenty months after the first surgery, MRI revealed local recurrence of the tumor and subtotal resection was performed.
脑膜黑素细胞瘤是一种罕见的颅内肿瘤，在桥小脑角（CPA）极为罕见。这些肿瘤通常被认为是良性的，因为在组织学检查中缺乏恶性特征，但有几篇文献描述了肿瘤的恶性行为，如局部复发频率高、伴有软脑膜播散的恶性转化。我们描述了一例CPA区脑膜黑素细胞瘤病例并讨论了该肿瘤的特征。该病例为一名43岁女性，患有右侧CPA区轴外肿块，伴有眩晕和恶心。计算机断层扫描（CT）和磁共振成像（MRI）显示右侧CPA区有一肿块。该肿块在T1加权图像上呈高信号，在T2加权图像上呈低信号。进行了手术切除，病理诊断为脑膜黑素细胞瘤。首次手术后20个月，MRI显示肿瘤局部复发，遂进行了次全切除。
