Department of Pediatrics, Buddhist Tzu-Chi General Hospital, Hualien, Taiwan.
Pediatr Infect Dis J. 2012 Jan;31(1):100-1. doi: 10.1097/INF.0b013e3182309ec0.
Chronic granulomatous disease is a genetic disorder characterized by defects in the ability of the phagocytes to kill ingested microbes, leading to recurrent bacterial and fungal infections. Vertebral osteomyelitis complicated by an epidural abscess from aspergillosis is rare. We report a case of Aspergillus spondylodiscitis with an epidural abscess in a 17-year-old autosomal recessive chronic granulomatous disease patient.
慢性肉芽肿病是一种遗传性疾病，其特征是吞噬细胞杀灭吞噬微生物的能力缺陷，导致反复发生细菌和真菌感染。曲霉菌引起的脊椎骨髓炎合并硬膜外脓肿较为罕见。我们报告一例 17 岁常染色体隐性遗传慢性肉芽肿病患者发生曲霉菌性脊椎骨和椎间盘炎合并硬膜外脓肿。
