Miyagawa S, Makuuchi M, Lygidakis N J, Noguchi T, Nishimaki K, Hashikura Y, Harada H, Hayashi K, Kakazu T
First Department of Surgery, Shinshu University, School of Medicine, Asahi Matsumoto, Japan.
Hepatogastroenterology. 1992 Oct;39(5):381-4.
Reconstructive methods following pancreaticoduodenectomy in our department are discussed and evaluated in this study. Between January 1980 and November 1990 fifty-two consecutive patients underwent pancreaticoduodenectomy because of pancreas head disease. Thirty-one patients underwent pancreaticojejunostomy and twenty-one had pancreaticogastrostomy as reconstructive procedures. Mortality rate was 6% in pancreaticojejunstomy versus zero in pancreaticogastrostomy. Six patients had leakage from the pancreaticojejunostomy, but only one patient had necrosis of the gastric stump and leakage from the pancreaticogastrostomy. This case had previous distal gastrectomy done for gastric ulcer. The residual stomach might not have been large enough, and the blood supply of the gastric stump might not have been adequate for pancreaticogastrostomy. Except for this case, none was observed with leakage from the pancreatic anastomosis in the pancreaticogastrostomy group. No statistical significance in operating time or blood loss was observed between the two methods. The pancreaticogastrostomy cases without complications had significantly less loss of body weight than those with pancreaticojejunostomy at the date of discharge (p < 0.05). It is concluded that pancreaticogastrostomy is the safer reconstructive method following pancreaticoduodenectomy, although it may not be indicated in patients with prior gastrectomy.
本研究对我院胰十二指肠切除术后的重建方法进行了讨论和评估。1980年1月至1990年11月,52例因胰头疾病连续接受胰十二指肠切除术的患者,31例行胰空肠吻合术,21例行胰胃吻合术作为重建手术。胰空肠吻合术的死亡率为6%,而胰胃吻合术的死亡率为零。6例胰空肠吻合术患者出现吻合口漏,但胰胃吻合术仅有1例胃残端坏死及吻合口漏。该病例曾因胃溃疡行远端胃切除术,残余胃可能不够大,胃残端血供可能不足以行胰胃吻合术。除该病例外,胰胃吻合术组未观察到胰吻合口漏。两种方法在手术时间和失血量方面无统计学差异。无并发症的胰胃吻合术患者出院时体重减轻明显少于胰空肠吻合术患者(p<0.05)。结论:胰胃吻合术是胰十二指肠切除术后更安全的重建方法,尽管既往有胃切除术的患者可能不适用。