Bessad A, Mouloua K, Kherrachi I, Benbetka S, Benikhlef R, Mezai G, Harrat Z
Institut des sciences vétérinaires, université Saad-Dahleb de Blida, Blida, Algérie.
Bull Soc Pathol Exot. 2012 Feb;105(1):5-7. doi: 10.1007/s13149-011-0182-4. Epub 2011 Aug 27.
In the north of Algeria, Leishmania infantum is responsible for two clinical forms of leishmaniasis: visceral and cutaneous leishmaniasis, for which dogs are the only proven reservoir host. In this study, the authors report, for the first time, the isolation of L. infantum from a golden jackal (Canis aureus) trapped in the Illoulen ou Malou region (Grande Kabylie). Two isolates were thus obtained from bone marrow and spleen and were identified by starch gel isoenzyme electrophoresis as L. infantum MON-1, the widespread zymodeme in the north of the country. Leishmania parasites have also been detected by polymerase chain reaction (PCR) in the biopsy of the spleen. The golden jackal, a prevalent wild canid in Northern Africa, could play a predominant role in the sylvatic foci of leishmaniasis and in the dissemination of the parasite in this region.
在阿尔及利亚北部，婴儿利什曼原虫是两种临床型利什曼病的病原体：内脏利什曼病和皮肤利什曼病，狗是唯一经证实的储存宿主。在本研究中，作者首次报告从伊卢伦乌马卢地区（大卡比利亚）捕获的一只金豺（金豺属）体内分离出婴儿利什曼原虫。从骨髓和脾脏中获得了两个分离株，并通过淀粉凝胶同工酶电泳鉴定为婴儿利什曼原虫MON-1，这是该国北部广泛存在的酶带型。通过聚合酶链反应（PCR）在脾脏活检中也检测到了利什曼原虫寄生虫。金豺是北非一种常见的野生犬科动物，可能在利什曼病的自然疫源地以及该地区寄生虫的传播中起主要作用。
