Kogan M I, Belousov I I, Bolotskov A S
Urologiia. 2011 May-Jun(3):22-8.
Causes and mechanisms of chronic pelvic pain/chronic prostatitis (CPP/CP) syndrome are not well investigated yet. It is suggested that pain in an inflammatory form of this syndrome may be due to tissue inflammation. In the non-inflammatory form pain may result from neurogenic factors. Standard diagnostic methods in the absence of inflammation often fail to detect pathological changes in the prostate. We made duplex mapping of the prostate and obtained quantitative characteristics of arterial hemodynamics of the prostate. Control values of arterial prostatic blood flow were developed after examination of healthy volunteers. These values were compared with similar values of arterial blood flow in CPP/CP syndrome. We found a significant decrease of the peak systolic velocity in patients with non-inflammatory CPP/CP syndrome. There is a direct correlation between intensity of pain syndrome and peak systolic velocity of arterial blood flow. Thus, pain may arise from chronic prostatic ischemia.
慢性盆腔疼痛/慢性前列腺炎（CPP/CP）综合征的病因和机制尚未得到充分研究。有人认为，该综合征炎症形式的疼痛可能是由于组织炎症。在非炎症形式中，疼痛可能由神经源性因素引起。在没有炎症的情况下，标准诊断方法往往无法检测到前列腺的病理变化。我们对前列腺进行了双功超声成像，并获得了前列腺动脉血流动力学的定量特征。在对健康志愿者进行检查后，得出了前列腺动脉血流的对照值。将这些值与CPP/CP综合征患者的动脉血流相似值进行了比较。我们发现，非炎症性CPP/CP综合征患者的收缩期峰值流速显著降低。疼痛综合征的强度与动脉血流的收缩期峰值流速之间存在直接相关性。因此，疼痛可能源于慢性前列腺缺血。
