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加拿大年轻人哮喘患病率的城乡差异:健康行为和肥胖的作用。

Urban-rural differences in asthma prevalence among young people in Canada: the roles of health behaviors and obesity.

机构信息

Canadian Centre for Health and Safety in Agriculture, University of Saskatchewan, Saskatoon, SK, Canada.

出版信息

Ann Allergy Asthma Immunol. 2011 Sep;107(3):220-8. doi: 10.1016/j.anai.2011.06.014. Epub 2011 Jul 22.

Abstract

BACKGROUND

Asthma prevalence has been reported to be lower in rural regions, but the reasons for this are not known.

OBJECTIVE

To confirm the existence of an urban-rural geographic gradient in asthma prevalence among Canadian youths and to evaluate whether this gradient was mediated by health behaviors.

METHODS

Cross-sectional data from 4,726 Canadian youth (grades 6-10) were collected during the 2001-02 Health Behaviour in School-Aged Children survey. Geographic region was categorized as metro (urbanized), non-metro but adjacent to metro, and rural. Asthma was defined via self-report of doctors' diagnoses and at least 1 of: (1) asthma symptoms or (2) a health care visit for asthma in the past year. Health behaviors (diet and physical activity) as well as obesity were also assessed.

RESULTS

Asthma prevalence was lowest in rural regions (metro = 17.7%, non-metro-adjacent = 15.6%, rural = 14.8%). A lower risk of asthma was associated with rural region (adjusted odds ratio [OR] = 0.76, 95% CI = 0.61-0.95) and living in non-metro-adjacent regions (adjusted OR = 0.81, 95% CI = 0.65-1.01). Health behaviors and obesity status did not mediate the association between geographic region and asthma. Being overweight or obese, having a high physical activity level, and exposure to passive smoking independently elevated the risk of asthma, whereas increased consumption of whole milk or vegetables were each protective.

CONCLUSIONS

Although asthma prevalence among youth was lower in rural areas, this association was not mediated by health behaviors or obesity. Other exposures, likely environmental, are the logical mechanisms through which rural geographic status is related to lower asthma prevalence.

摘要

背景

据报道,农村地区的哮喘患病率较低,但原因尚不清楚。

目的

确认加拿大青少年哮喘患病率存在城乡地理梯度,并评估这种梯度是否由健康行为介导。

方法

在 2001-02 年的“儿童健康行为调查”中,收集了 4726 名加拿大青少年(6-10 年级)的横断面数据。地理区域分为市区(城市化)、非市区但毗邻市区和农村。哮喘通过医生诊断和以下至少一项来定义:(1)哮喘症状或(2)过去一年因哮喘就诊。还评估了健康行为(饮食和体育活动)以及肥胖情况。

结果

哮喘患病率在农村地区最低(市区为 17.7%,非市区毗邻为 15.6%,农村为 14.8%)。农村地区哮喘风险较低(调整后的优势比[OR] = 0.76,95%可信区间[CI] = 0.61-0.95),居住在非市区毗邻地区(调整后的 OR = 0.81,95% CI = 0.65-1.01)也是如此。健康行为和肥胖状况并不能调节地理区域与哮喘之间的关系。超重或肥胖、高身体活动水平和被动吸烟暴露独立增加哮喘风险,而增加全脂牛奶或蔬菜的摄入量则具有保护作用。

结论

尽管农村地区青少年的哮喘患病率较低,但这种关联与健康行为或肥胖无关。其他暴露,可能是环境暴露,是农村地理状况与较低哮喘患病率相关的合理机制。

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