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老年人参与和参与社区环境中跌倒预防干预措施的情况:对 Cochrane 系统评价的补充。

Older people's participation in and engagement with falls prevention interventions in community settings: an augment to the Cochrane systematic review.

机构信息

School of Health and Social Care, University of Reading, Reading, Berkshire, UK.

出版信息

Age Ageing. 2012 Jan;41(1):16-23. doi: 10.1093/ageing/afr103. Epub 2011 Aug 28.

DOI:10.1093/ageing/afr103
PMID:21875865
Abstract

BACKGROUND

Randomised controlled trials (RCTs) of fall prevention conducted in community settings have recently been systematically reviewed.

OBJECTIVE

To augment this review by analysing older people's participation in the trials and engagement with the interventions.

DESIGN

Review of the 99 single and multifactorial RCTs included in the Cochrane systematic review of falls prevention interventions.

SETTING

Community.

PARTICIPANTS

Adults aged 60+/mean age minus one standard deviation of 60+.

METHODS

Calculated aggregate data on recruitment (proportion who accepted the invitation to participate), attrition at 12 month follow-up (loss of participants), adherence (to intervention protocol) and whether adherence moderated the effect of interventions on trial outcomes.

RESULTS

The median recruitment rate was 70.7% (64.2-81.7%, n = 78). At 12 months the median attrition rate including mortality was 10.9% (9.1-16.0%, n = 44). Adherence rates (n = 69) were ≥80% for vitamin D/calcium supplementation; ≥70% for walking and class-based exercise; 52% for individually targeted exercise; approximately 60-70% for fluid/nutrition therapy and interventions to increase knowledge; 58-59% for home modifications; but there was no improvement for medication review/withdrawal of certain drugs. Adherence to multifactorial interventions was generally ≥75% but ranged 28-95% for individual components. The 13 studies that tested for whether adherence moderated treatment effectiveness produced mixed results.

CONCLUSIONS

Using median rates for recruitment (70%), attrition (10%) and adherence (80%), we estimate that, at 12 months, on average half of community-dwelling older people are likely to be adhering to falls prevention interventions in clinical trials.

摘要

背景

最近对社区环境中进行的预防跌倒的随机对照试验(RCT)进行了系统评价。

目的

通过分析老年人参与试验和参与干预的情况来扩充该综述。

设计

对Cochrane 预防跌倒干预措施系统评价中包含的 99 项单一和多因素 RCT 进行综述。

设置

社区。

参与者

年龄 60 岁及以上的成年人(平均年龄减去 60 岁的一个标准差)。

方法

计算了招募方面的综合数据(接受参与邀请的比例)、12 个月随访时的失访率(参与者流失)、依从性(对干预方案的依从性)以及依从性是否会影响干预措施对试验结果的影响。

结果

中位招募率为 70.7%(64.2-81.7%,n=78)。12 个月时,包括死亡率在内的中位失访率为 10.9%(9.1-16.0%,n=44)。依从率(n=69)≥80%的有维生素 D/钙补充剂;≥70%的有散步和基于课堂的运动;52%的有针对性的个体运动;约 60-70%的有液体/营养治疗和提高知识的干预措施;58-59%的有家庭改造;但药物审查/停用某些药物并未得到改善。多因素干预的依从性通常≥75%,但个别成分的范围为 28-95%。测试依从性是否调节治疗效果的 13 项研究得出了混合结果。

结论

根据招募(70%)、失访(10%)和依从性(80%)的中位数率,我们估计,在 12 个月时,平均有一半的社区居住的老年人可能会在临床试验中坚持预防跌倒的干预措施。

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