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巴尔的摩市住院艾滋病毒患者中无症状细菌性性传播感染的患病率。

Prevalence of asymptomatic bacterial sexually transmitted infections in hospitalized HIV patients in Baltimore City.

作者信息

Hodowanec Aimee, Nayak Seema, Charurat Manhattan, Vaughan Leroy, Kanno Mettassebia, Fantry Lori

机构信息

1Department of Medicine, Section of Infectious Diseases, Rush University Medical Center, Chicago, IL, USA.

出版信息

J Int Assoc Physicians AIDS Care (Chic). 2012 Jan-Feb;11(1):16-9. doi: 10.1177/1545109711418509. Epub 2011 Aug 29.

Abstract

Sexually transmitted infections (STIs) are known to promote the transmission of HIV. Diagnosing these infections can identify patients engaging in high-risk behaviors and provides an opportunity for intervention and education. The Centers for Disease Control and Prevention (CDC) recommends STI screening as part of routine HIV care. Ninety HIV-infected inpatients admitted to the University of Maryland Hospital were screened for gonorrhea, chlamydia, and syphilis. None of the nucleic acid amplification probes were positive for gonorrhea, and 1 was positive for chlamydia. A total of 8 rapid plasma reagin (RPR) tests were positive, 2 of which are believed to be associated with new infection or treatment failure. Rapid plasma reagin positivity was found to be associated with men who have sex with men (MSM), low CD4 count, and high HIV viral load. Routine inpatient screening for asymptomatic STIs in HIV-infected patients may be beneficial, particularly patients not engaged in routine outpatient care.

摘要

已知性传播感染(STIs)会促进艾滋病毒的传播。诊断这些感染可以识别出有高危行为的患者,并提供干预和教育的机会。疾病控制与预防中心(CDC)建议将性传播感染筛查作为常规艾滋病毒护理的一部分。对入住马里兰大学医院的90名艾滋病毒感染住院患者进行了淋病、衣原体和梅毒筛查。核酸扩增探针检测淋病均为阴性,衣原体检测有1例呈阳性。快速血浆反应素(RPR)检测共有8例呈阳性,其中2例被认为与新感染或治疗失败有关。发现快速血浆反应素阳性与男男性行为者(MSM)、低CD4计数和高艾滋病毒病毒载量有关。对艾滋病毒感染患者进行无症状性传播感染的常规住院筛查可能有益,尤其是那些未接受常规门诊护理的患者。

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