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小切口白内障手术后的内皮细胞丢失

Endothelial cell loss after small incision cataract surgery.

作者信息

Thakur S Kd, Dan A, Singh M, Banerjee A, Ghosh A, Bhaduri G

机构信息

Regional Institute of Ophthalmology, Kolkata, West Bengal, India.

出版信息

Nepal J Ophthalmol. 2011 Jul-Dec;3(2):177-80. doi: 10.3126/nepjoph.v3i2.5273.

DOI:10.3126/nepjoph.v3i2.5273
PMID:21876594
Abstract

BACKGROUND

The corneal endothelium plays an important role in maintaining the dehydrated state and the transparency of the cornea. Some degree of endothelial cell loss invariably occurs in all types of cataract surgery but the amount of endothelial cell loss varies with the surgical technique.

AIM

To evaluate the density of the central corneal endothelial cells before and after small incision cataract surgery (SICS) with posterior chamber intraocular lens (PC IOL) implantation.

MATERIALS AND METHODS

A total of 100 eyes of 100 patients undergoing SICS with PC IOL were included in the study. Endothelial cell density was measured with non-contact specular microscope pre-operatively and post-operatively on Day 1, Day 7 and at one month.

RESULTS

The mean endothelial cell count pre-operatively was 2673 ± 358.85 cells / sq mm while post-operatively at 1 month it was 2249.77 ± 354.04 cells / sq mm.

CONCLUSION

There is 15.83 % reduction in endothelial cell count after SICS with PC IOL implantation, which is comparable with other modes of cataract surgery like extra-capsular cataract extraction and phacoemulsification.

摘要

背景

角膜内皮在维持角膜的脱水状态和透明度方面发挥着重要作用。在所有类型的白内障手术中,都会不可避免地出现一定程度的内皮细胞丢失,但内皮细胞丢失的量会因手术技术而异。

目的

评估小切口白内障手术(SICS)联合后房型人工晶状体(PC IOL)植入术前、后的中央角膜内皮细胞密度。

材料与方法

本研究纳入了100例行SICS联合PC IOL植入术的患者的100只眼。术前及术后第1天、第7天和1个月时,使用非接触式角膜内皮显微镜测量内皮细胞密度。

结果

术前平均内皮细胞计数为2673±358.85个/平方毫米,术后1个月时为2249.77±354.04个/平方毫米。

结论

SICS联合PC IOL植入术后内皮细胞计数减少了15.83%,这与其他白内障手术方式如囊外白内障摘除术和超声乳化白内障吸除术相当。

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