牙买加人群中梅毒血清学检测的生物学假阳性
Biological false positive serological tests for syphilis in the Jamaican population.
作者信息
Smikle M F, James O B, Prabhakar P
机构信息
Department of Microbiology, University of the West Indies, Kingston, Jamaica.
出版信息
Genitourin Med. 1990 Apr;66(2):76-8. doi: 10.1136/sti.66.2.76.
Abstract
A total of 19,067 sera were screened for biological false positive (BFP) reactivity by the Venereal Disease Research Laboratory (VDRL) test. Sera which were reactive in the VDRL test were confirmed by the fluorescent treponemal antibody absorption (FTA-ABS) test. BFP reactions were detected in 0.59% of the general population, 0.72% of pregnant women and 11.8% of patients with systemic lupus erythematosus (SLE). The rate of BFP reactors among pregnant women did not differ significantly from the general population. The female to male ratio of BFP in the general population was 2:1 whilst that in the group of patients with SLE was 8:1. The overall seroprevalence of syphilis was 2.2%.
摘要
通过性病研究实验室（VDRL）试验对总共19067份血清进行了生物假阳性（BFP）反应性筛查。VDRL试验呈反应性的血清通过荧光密螺旋体抗体吸收（FTA-ABS）试验进行确认。在普通人群中检测到BFP反应的比例为0.59%，孕妇为0.72%，系统性红斑狼疮（SLE）患者为11.8%。孕妇中BFP反应者的比例与普通人群无显著差异。普通人群中BFP的男女比例为2:1，而SLE患者组为8:1。梅毒的总体血清阳性率为2.2%。
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