Hossain A
Genitourin Med. 1986 Oct;62(5):293-7. doi: 10.1136/sti.62.5.293.
A total of 6684 sera were initially screened for syphilis by the Venereal Disease Research Laboratory (VDRL) test and the Treponema pallidum haemagglutination assay (TPHA). Reactive sera from either or both these tests were tested for confirmation by the fluorescent treponemal antibody-absorbed (FTA-ABS) test. VDRL biological false positive reactors were detected in 0.5% of the total sera examined, with 0.4% and 0.8%, respectively, obtained in pregnant women and blood donors. Eight sera (0.1%) were found to be positive in the TPHA test alone. An overall positivity of 2.7% for syphilis was detected, with a 0.85% positivity in antenatal patients. Infection with T pallidum seemed to be more common in men than in women (1.6:1) and predominated in the age group 20-39 years. Serological testing of sera from 26 mother and infant pairs allowed one case of congenital syphilis to be detected by FTA-ABS (IgM) and identified VDRL biological false positivity in seven infants.
最初，采用性病研究实验室（VDRL）试验和梅毒螺旋体血凝试验（TPHA）对总共6684份血清进行梅毒筛查。对这两种试验中单项或两项呈反应性的血清，采用荧光螺旋体抗体吸收（FTA-ABS）试验进行确诊检测。在所检测的全部血清中，VDRL生物学假阳性反应者占0.5%，孕妇和献血者中分别为0.4%和0.8%。发现8份血清（0.1%）仅在TPHA试验中呈阳性。梅毒总体阳性率为2.7%，产前患者阳性率为0.85%。梅毒螺旋体感染在男性中似乎比女性更常见（1.6:1），且在20至39岁年龄组中占主导。对26对母婴的血清进行血清学检测，通过FTA-ABS（IgM）检测出1例先天性梅毒，并在7名婴儿中鉴定出VDRL生物学假阳性。
