Mikhin V P, Kharchenko A V, Rosliakova E A, Cherniatina M A
Kardiologiia. 2011;51(6):26-31.
We studied effect of coenzyme Q(10) on 24-hour blood pressure profile and function of vascular endothelium in patients with essential hypertension. Coenzyme Q(10) was used as a component of combination therapy comprising angiotensin converting enzyme inhibitor enalapril. Administration of coenzyme Q(10) in combination with traditional antihypertensive therapy promoted normalization of vascular endothelial function and more effective correction of 24-hour blood pressure profile. These findings allow to consider the use of coenzyme Q(10) as promising component of combination therapy of arterial hypertension.
我们研究了辅酶Q10对原发性高血压患者24小时血压谱及血管内皮功能的影响。辅酶Q10作为包含血管紧张素转换酶抑制剂依那普利的联合治疗的组成部分使用。将辅酶Q10与传统抗高血压治疗联合应用可促进血管内皮功能正常化，并更有效地改善24小时血压谱。这些发现使得可以考虑将辅酶Q10作为动脉高血压联合治疗中有前景的组成部分。
