Department of Clinical Veterinary Science, University of Bristol, UK.
Equine Vet J. 2012 May;44(3):259-66. doi: 10.1111/j.2042-3306.2011.00385.x. Epub 2011 Aug 26.
There are numerous treatments for correction of dorsal displacement of the soft palate (DDSP). However, the efficacy of these treatments is controversial and there is little consensus on how best to treat this condition. The aims of this study were to systematically review the literature and to assess the evidence on the clinical effects of interventions for dynamic intermittent DDSP. A secondary objective was to assess whether factors relating to study quality affected reported success rates. Twenty-three studies were included, covering a wide number of interventions but also differing widely is terms of study design, sample size, method of diagnosis, outcome measure and the number lost to follow-up. The assessment of adverse effects was severely limited because of lack of reporting. The way in which success is measured appears to have a great effect on the reported results. Research synthesis has been severely limited because of the heterogeneity in the included studies. The low level of evidence makes it difficult to draw firm conclusions as to the efficacy of procedures for DDSP. Hence it is currently not possible to determine which procedure is the most appropriate. This systematic review highlights the difficulties of studying palatal dysfunction and suggests areas where improvements can be made in future studies.
有许多治疗方法可用于纠正硬腭后移位（DDSP）。然而，这些治疗方法的疗效存在争议，对于如何最好地治疗这种情况，尚无共识。本研究的目的是系统地回顾文献，并评估干预措施对动态间歇性 DDSP 的临床效果的证据。次要目标是评估与研究质量相关的因素是否会影响报告的成功率。共纳入 23 项研究，涵盖了多种干预措施，但在研究设计、样本量、诊断方法、结局测量以及失访数量方面差异很大。由于报告不足，对不良影响的评估受到严重限制。由于报告结果的方式存在很大差异，成功的衡量标准似乎对报告结果有很大影响。由于纳入研究的异质性，研究综合受到严重限制。证据水平低使得难以确定 DDSP 程序的疗效。因此，目前尚无法确定哪种程序最合适。本系统评价突出了研究腭功能障碍的困难，并提出了未来研究中可以改进的领域。
