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采用逆行面神经解剖技术手术切除腮腺多形性腺瘤后的肿瘤复发情况。

Tumour recurrence after surgical removal of parotid pleomorphic salivary adenoma using a retrograde facial nerve dissection technique.

作者信息

O'Regan Barry, Bharadwaj Girish

机构信息

Maxillofacial Unit, Queen Margaret Hospital, Whitefield Road, Dunfermline, Fife KY12 0SU, United Kingdom.

出版信息

Br J Oral Maxillofac Surg. 2012 Jul;50(5):417-9. doi: 10.1016/j.bjoms.2011.08.002. Epub 2011 Aug 30.

Abstract

Recurrence after surgical removal of parotid pleomorphic salivary adenoma using retrograde facial nerve dissection is not well researched. We adopted retrograde nerve dissection for parotid surgery for benign disease as a standard procedure in 1995. The objective of this study was to establish the rate of recurrence of primary tumours associated with the technique after removal of parotid pleomorphic salivary adenoma. We recruited 59 patients over a 16-year (1995-2011) period and collected the data prospectively. Eight patients were excluded as they had died or had been lost to follow up. Male:female ratio was 16:35 and age range was 15-69 years. The mean tumour size as measured on magnetic resonance imaging (MRI) was 27.4mm. Thirty-eight patients had superficial parotidectomy, 8 had total parotidectomy, and 5 had partial superficial parotidectomy. Mean follow up from the date of operation was 104 months (median 98, range 17-171). All patients were reviewed and examined in 2011 to establish whether the tumour had recurred. One patient had developed a solitary nodular recurrence 8 years after the initial procedure. Recurrence was 2%. The rate of clinically apparent recurrence after parotidectomy for pleomorphic salivary adenoma in this study is low and is comparable with others reported.

摘要

采用逆行面神经解剖术手术切除腮腺多形性腺瘤后的复发情况尚未得到充分研究。1995年,我们将逆行神经解剖术用于腮腺良性疾病手术作为标准术式。本研究的目的是确定腮腺多形性腺瘤切除术后与该技术相关的原发肿瘤复发率。我们在16年(1995 - 2011年)期间招募了59例患者,并前瞻性地收集数据。8例患者因死亡或失访被排除。男女比例为16:35,年龄范围为15 - 69岁。磁共振成像(MRI)测量的平均肿瘤大小为27.4mm。38例行浅叶腮腺切除术,8例行全腮腺切除术,5例行部分浅叶腮腺切除术。从手术日期起的平均随访时间为104个月(中位数98个月,范围17 - 171个月)。2011年对所有患者进行复查和检查,以确定肿瘤是否复发。1例患者在初次手术后8年出现孤立结节状复发。复发率为2%。本研究中腮腺多形性腺瘤腮腺切除术后临床明显复发率较低,与其他报道相当。

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