Duke University, Department of Biomedical Engineering, Injury Biomechanics Laboratory, Durham, NC 27708-0281, USA.
Forensic Sci Int. 2012 Jan 10;214(1-3):167-72. doi: 10.1016/j.forsciint.2011.07.050. Epub 2011 Aug 30.
Radiologic imaging is crucial in the diagnosis of skull fracture, but there is some doubt as to whether different imaging modalities can accurately identify fractures present on a human skull. While studies have been performed to evaluate the efficacy of radiologic imaging at other anatomical locations, there have been no systematic studies comparing various CT techniques, including high resolution imaging with and without 3D reconstructions to conventional radiologic imaging in children, we investigated which imaging modalities: high-resolution CT scan with 3D projections, clinical-resolution CT scans or X-rays, best showed fracture occurrence in a pediatric human cadaver skull by having an expert pediatric radiologist examine radiologic images from fractured skulls. The skulls used were taken from pediatric cadavers ranging in age from 5 months to 16 years. We evaluated the sensitivity and specificity for the imaging modalities using dissection findings as the gold standard. We found that high-resolution CT scans with 3D projections and conventional CT provided the most accurate fracture diagnosis (single-fracture sensitivity of 71%) followed by X-rays (single-fracture sensitivity of 63%). Linear fractures outsider the region of the sutures were more identifiable than diastatic fractures, though the incidence of false positives was greater for linear fractures. In the two cases where multiple fractures were present on the same anatomical skull location, the radiologist was less likely to identify the presence of additional fractures than a single fracture. Overall, the high-resolution and clinical-resolution CT scans had the similar accuracy for detecting skull fractures while the use of the X-ray was both less accurate and had a lower specificity.
放射影像学在诊断颅骨骨折中至关重要,但对于不同的成像方式是否能准确识别人类颅骨上的骨折存在一些疑问。虽然已经有研究评估了放射影像学在其他解剖部位的效果,但尚未有系统的研究比较各种 CT 技术,包括高分辨率成像与 3D 重建与传统放射影像学在儿童中的效果,我们研究了哪种成像方式:高分辨率 CT 扫描加 3D 投影、临床分辨率 CT 扫描或 X 射线,通过让一位有经验的儿科放射科医生检查颅骨骨折的放射图像,最好地显示出儿童尸体颅骨中的骨折发生情况。使用的颅骨取自年龄在 5 个月至 16 岁之间的儿童尸体。我们使用解剖发现作为金标准,评估了这些成像方式的敏感性和特异性。我们发现高分辨率 CT 扫描加 3D 投影和常规 CT 对骨折的诊断最准确(单发骨折的敏感性为 71%),其次是 X 射线(单发骨折的敏感性为 63%)。位于缝合区域之外的线性骨折比分离性骨折更容易识别,尽管线性骨折的假阳性率更高。在两个相同解剖颅骨位置存在多处骨折的情况下,放射科医生识别额外骨折的可能性低于识别单一骨折。总的来说,高分辨率和临床分辨率 CT 扫描在检测颅骨骨折方面具有相似的准确性,而 X 射线的准确性较低且特异性较低。