Department of Breast Surgery, Murakami Memorial Hospital, Asahi University, Gifu, Japan.
Eur J Surg Oncol. 2011 Nov;37(11):950-5. doi: 10.1016/j.ejso.2011.07.006. Epub 2011 Aug 30.
The aim of this study was to evaluate the accuracy of a magnetic resonance imaging (MRI) marking technique with a drape-type thermoplastic shell for planning breast-conserving surgery (BCS).
A prospective review was performed on 35 consecutive patients who underwent MRI in the supine position and used the specified MRI marking technique. Eleven cases underwent pre-operative chemotherapy and 24 cases did not. After immobilizing the breast mound with a drape-type thermoplastic shell, patients underwent MRI, and the location of the lesion was marked on the shell. Resection lines were dyed blue by indigo carmine, which was pushed through the pores of the shell. Specimens obtained during BCS were sliced into 5-mm contiguous sections, and the margin was assessed for each specimen. Cancer foci less than 5 mm from the margin were classified as positive.
Of 35 patients, 33 were included in the analysis; 2 were excluded due to a lack of effect of pre-operative chemotherapy. Of these 33 patients, 25 (75.8%) had negative margins and 7 (21.2%) had positive margins.
Our MRI marking technique may be useful for evaluating the extent of tumors that were determined by MRI alone. Long-term outcomes of this technique should be evaluated further.
本研究旨在评估一种带有帘式热塑壳的磁共振成像（MRI）标记技术在规划保乳手术（BCS）中的准确性。
对 35 例连续接受仰卧位 MRI 检查并采用特定 MRI 标记技术的患者进行前瞻性回顾。11 例患者接受术前化疗，24 例患者未接受。在使用帘式热塑壳固定乳房丘后，患者接受 MRI 检查，并在壳上标记病变位置。靛胭脂通过壳上的孔被推注到乳房组织中，使切痕线染上蓝色。在 BCS 中获得的标本被切成 5mm 的连续切片，对每个标本的边缘进行评估。距离边缘小于 5mm 的癌灶被归类为阳性。
在 35 例患者中，33 例纳入分析；2 例因术前化疗效果不佳而被排除。在这 33 例患者中，25 例（75.8%）边缘阴性，7 例（21.2%）边缘阳性。
我们的 MRI 标记技术可能有助于评估单独 MRI 确定的肿瘤范围。应进一步评估该技术的长期结果。
