中国慢性肾脏病住院患者心血管疾病分析

Analysis of cardiovascular disease in Chinese inpatients with chronic kidney disease.

作者信息

Chen Xiao-Nong, Pan Xiao-Xia, Yu Hai-Jin, Shen Ping-Yan, Zhang Qian-Ying, Zhang Wen, Ren Hong, Qian Ying, Zhu Ping, Chen Nan

机构信息

Department of Nephrology, Ruijin Hospital affiliated to Shanghai Jiaotong University, School of Medicine, PR China.

出版信息

Intern Med. 2011;50(17):1797-801. doi: 10.2169/internalmedicine.50.5158. Epub 2011 Sep 1.

DOI:10.2169/internalmedicine.50.5158

PMID:21881277

Abstract

OBJECTIVE

To investigate the prevalence of cardiovascular disease (CVD) in a Chinese patient population with different stages of chronic kidney disease (CKD).

METHODS

Six hundred and two CKD patients who were hospitalized in Ruijin Hospital between Jan. 2004 and Jan. 2006 were selected. Patients' medical histories and the results of laboratory tests were reviewed.

RESULTS

The prevalence of CVD in 602 patients with CKD stages 1 to 5 was 1.28%, 17.24%, 22.86%, 33.33%, 56.2% respectively. The prevalence of CVD in CKD stage 5 patients with dialysis was 78.51%. In all the patients, the prevalence of coronary artery disease (CAD), left ventricular hypertrophy (LVH), and congestive heart failure (CHF) was 8.64% (52/602), 26% (154/602), and 13% (78/602), respectively. Regarding co-morbidities of CVD, 34.52% of patients had 2 or more of the above abnormalities. The prevalence of CAD in patients with CKD stages 1 to 5 respectively was 1.28%, 5.75%, 7.86%, 10.26%, 12.33%;LVH was 0%, 11.49%, 16.43%, 29.49%, 44.75%; and CHF was 0%, 3.45%, 3.57%, 8.97%, 28.77%.

CONCLUSION

The occurrence of CVD started from CKD stage 1 and increased with the progression of CKD. The screening and prevention of CVD should begin at CKD stage 1.

摘要

目的

调查不同慢性肾脏病（CKD）阶段的中国患者群体中心血管疾病（CVD）的患病率。

方法

选取2004年1月至2006年1月在瑞金医院住院的602例CKD患者。回顾患者的病史及实验室检查结果。

结果

602例CKD 1至5期患者的CVD患病率分别为1.28%、17.24%、22.86%、33.33%、56.2%。CKD 5期透析患者的CVD患病率为78.51%。在所有患者中，冠状动脉疾病（CAD）、左心室肥厚（LVH）和充血性心力衰竭（CHF）的患病率分别为8.64%（52/602）、26%（154/602）和13%（78/602）。关于CVD的合并症，34.52%的患者有2种或更多上述异常。CKD 1至5期患者的CAD患病率分别为1.28%、5.75%、7.86%、10.26%、12.33%；LVH患病率分别为0%、11.49%、16.43%、29.49%、44.75%；CHF患病率分别为0%、3.45%、3.57%、8.97%、28.77%。