Leggott P J
Oral AIDS Center, University of California, San Francisco.
NCI Monogr. 1990(9):129-32.
A number of acute oral complications may be associated with cancer therapy in children, but the extent and duration of these complications, and the most effective management techniques. have not been well described. The few studies differ in design, making comparisons difficult. Well-controlled, prospective clinical studies are needed to define the most effective strategies for the management of acute oral complications in children. However, it is clear that dental intervention prior to cancer therapy is an important factor in the optimal preparation of the patient. During cancer therapy, intensive supervised oral preventive protocols appear to be of benefit to the child's oral health, overall comfort, and well-being. Furthermore, the prevention of oral infection may significantly reduce the morbidity associated with cancer therapy. Long-term preventive oral care may help prevent dental disease and infection in medically compromised children and contribute to improving the quality of life.
一些急性口腔并发症可能与儿童癌症治疗有关，但这些并发症的程度和持续时间以及最有效的管理技术尚未得到充分描述。少数研究在设计上存在差异，难以进行比较。需要开展严格控制的前瞻性临床研究，以确定治疗儿童急性口腔并发症的最有效策略。然而，很明显，癌症治疗前的牙科干预是患者最佳准备的一个重要因素。在癌症治疗期间，强化的、有监督的口腔预防方案似乎有利于儿童的口腔健康、整体舒适度和幸福感。此外，预防口腔感染可能会显著降低与癌症治疗相关的发病率。长期的预防性口腔护理可能有助于预防医疗条件较差儿童的牙齿疾病和感染，并有助于提高生活质量。
