Sattarzadeh R, Maleki M, Jamalian A, Amirpour A, Firuzi A, Samiei N, Esmaeilzadeh M, Ghorbani A, Tavoosi A
Department of Cardiology, Tehran University of Medical Sciences, Imam Khomeini Hospital, Tehran, Iran.
Cardiovasc J Afr. 2011 Jul-Aug;22(4):182-5. doi: 10.5830/CVJA-2010-061.
This study aimed at evaluating the early effects of successful elective percutaneous coronary intervention (PCI) on systolic and diastolic function.
We consecutively studied the systolic and diastolic function in 21 patients with stable coronary artery disease (CAD) and left ventricular ejection fraction (LVEF) > 40% before and 48 hours after successful elective PCI.
Tei index and systolic indices (LVEF, regional wall motion abnormality score, tricuspid annular plane systolic excursion and peak systolic velocity of mitral and tricuspid annulus) did not change significantly. Among the diastolic indices, only velocity propagation (Vp) improved significantly (from 42.9 ± 10.8 to 51.8 ± 10.7, p-value = 0.008) following PCI. Diastolic velocities, E/A ratio, deceleration time (DT), early and late diastolic velocities of mitral annulus in TDI, pulmonary vein systolic (PVs) and diastolic flow velocity (PVd) did not show significant improvement.
Propagation velocity of mitral inflow was the earliest index to recover following successful PCI in patients with stable CAD.
本研究旨在评估成功的择期经皮冠状动脉介入治疗(PCI)对收缩和舒张功能的早期影响。
我们连续研究了21例稳定型冠状动脉疾病(CAD)且左心室射血分数(LVEF)>40%的患者在成功的择期PCI术前及术后48小时的收缩和舒张功能。
Tei指数和收缩指标(LVEF、室壁运动异常评分、三尖瓣环平面收缩期位移以及二尖瓣和三尖瓣环的收缩期峰值速度)无显著变化。在舒张指标中,PCI术后仅速度传播(Vp)显著改善(从42.9±10.8增至51.8±10.7,p值=0.008)。舒张速度、E/A比值、减速时间(DT)、组织多普勒成像中二尖瓣环的舒张早期和晚期速度、肺静脉收缩期(PVs)和舒张期流速(PVd)均未显示出显著改善。
在稳定型CAD患者中,成功的PCI术后二尖瓣血流传播速度是最早恢复的指标。