Nozari Younes, Oskouei Nader Jangi, Khazaeipour Zahra
Department of Cardiology, Tehran Heart Center, Tehran University of Medical Sciences, Iran.
Acta Med Iran. 2012;50(1):26-30.
Coronary artery disease is one of the most common causes of mortality and morbidity across the world. Its treatment includes medical treatment, coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI). The purpose of this study was to investigate the effect of PCI on echocardiographic findings of left ventricular (LV) systolic and diastolic function. 115 patients with coronary artery disease candidate for PCI were enrolled to our study. Echocardiography was done before PCI, the day after and 3-6 months later. LV systolic and diastolic function were measured and recorded. Echocardiographic finding compared with repeated measurement analysis. Mean age of the patients was 57.8 ± 8.38 years. The mean ejection fraction (EF) was (%40.52 ± 6.36) before, (%41.83 ± 7.14) the day after, and (%44.0 ± 7.89) 3-6 months after PCI. Diastolic dysfunction were mild to moderate before PCI, which in %74 (86 patients) were improved to mild dysfunction the day after PCI but not changed 3-6 months later (P<0.0001). PCI improved LV ejection fraction, and LV diastolic function in our patient's population.
冠状动脉疾病是全球最常见的死亡和发病原因之一。其治疗方法包括药物治疗、冠状动脉旁路移植术(CABG)和经皮冠状动脉介入治疗(PCI)。本研究的目的是探讨PCI对左心室(LV)收缩和舒张功能超声心动图表现的影响。115例拟行PCI的冠状动脉疾病患者纳入本研究。在PCI术前、术后第1天以及3 - 6个月后进行超声心动图检查。测量并记录左心室收缩和舒张功能。通过重复测量分析比较超声心动图结果。患者的平均年龄为57.8±8.38岁。PCI术前平均射血分数(EF)为(40.52%±6.36%),术后第1天为(41.83%±7.14%),术后3 - 6个月为(44.0%±7.89%)。PCI术前舒张功能障碍为轻度至中度,其中74%(86例患者)在PCI术后第1天改善为轻度功能障碍,但在术后3 - 6个月未发生变化(P<0.0001)。PCI改善了本研究患者群体的左心室射血分数和左心室舒张功能。