Carlson D E, Platt L D, Medearis A L, Horenstein J
Department of Obstetrics and Gynecology, University of Southern California School of Medicine, Women's Hospital, Los Angeles.
Obstet Gynecol. 1990 Jun;75(6):989-93.
Little has been written regarding the ultrasonographic quantification of polyhydramnios or its subsequent management. Therefore, we designed this study to define polyhydramnios using the amniotic fluid index of greater than 2 SDs above the mean for late second- to third-trimester pregnancies, or 24 cm or greater. One hundred twelve nondiabetic women referred to Women's Hospital, Los Angeles County/University of Southern California Medical Center with the descriptive diagnosis of polyhydramnios made by experienced ultrasonographers were included in the study. There was poor correlation between these descriptions and fetal outcome. Twenty-six were qualitatively described as having severe, 29 as moderate, and 57 as mild polyhydramnios. Forty-nine of the 112 patients met our definition of significant polyhydramnios by having an amniotic fluid index of 24 cm or more. This particular definition allowed the inclusion of all fetuses with serious structural defects and/or death. Seven patients had an amniotic fluid index less than 24 cm, but with the traditional quantitative definition of one pocket of 8 cm or more; none of these patients had poor fetal outcome. These data appear to suggest that the use of descriptive definitions of polyhydramnios or a single fluid pocket of 8 cm or greater should be discarded in favor of using an amniotic fluid index of 24 cm or more. Once the diagnosis of polyhydramnios is made, the patient should have a detailed sonographic evaluation, be offered cytogenetic studies, and have antepartum surveillance.
关于羊水过多的超声定量分析及其后续处理,相关文献报道较少。因此,我们开展了本研究,将孕晚期(孕中期至孕晚期)羊水指数大于均值2个标准差或24 cm及以上定义为羊水过多。本研究纳入了112例非糖尿病女性,她们因羊水过多的描述性诊断被转诊至洛杉矶县妇女医院/南加州大学医学中心,该诊断由经验丰富的超声检查医师做出。这些描述与胎儿结局之间的相关性较差。其中,26例被定性描述为重度羊水过多,29例为中度,57例为轻度。112例患者中有49例羊水指数达到24 cm或更高,符合我们对显著羊水过多的定义。这一特定定义涵盖了所有有严重结构缺陷和/或死亡的胎儿。7例患者羊水指数小于24 cm,但符合一个羊水池深度8 cm或更深的传统定量定义;这些患者均未出现不良胎儿结局。这些数据似乎表明,应摒弃羊水过多的描述性定义或单一羊水池深度8 cm及以上的定义,而采用羊水指数24 cm及以上的定义。一旦诊断为羊水过多,患者应接受详细的超声评估,进行细胞遗传学检查,并接受产前监测。