Department of Radiology, Patras University Hospital, School of Medicine, Rion, Greece.
Cardiovasc Intervent Radiol. 2011 Dec;34(6):1123-36. doi: 10.1007/s00270-011-0258-z. Epub 2011 Sep 1.
Percutaneous catheter-directed intra-arterial thrombolysis is a safe and effective method of treating acute and subacute lower limb ischemia, as long as accurate patient selection and procedural monitoring are ensured. Although larger, controlled trials are needed to establish the role of PTDs in ALI, mechanical thrombectomy could currently be applied combined with lytic infusion in selected cases where rapid recanalization is required or as a stand-alone therapy when the administration of thrombolytic agents is contraindicated.
经皮导管定向动脉内溶栓是治疗急性和亚急性下肢缺血的一种安全有效的方法，只要确保准确的患者选择和程序监测。尽管需要更大规模的对照试验来确定 PTD 在 ALI 中的作用，但在需要快速再通的情况下，机械血栓切除术可以结合溶栓输注应用于选定的病例，或者在使用溶栓药物禁忌时作为单独的治疗方法。
