Hoppu Kalle, Hogerzeil Hans V
Poison Information Centre, Helsinki University Central Hospital and Hospital for Children and Adolescents, Institute for Clinical Sciences, University of Helsinki, Helsinki, Finland.
Handb Exp Pharmacol. 2011;205:353-72. doi: 10.1007/978-3-642-20195-0_18.
About nine million children die every year before they reach the age of 5 years, of conditions largely amendable with existing medicines. Lack of medicines is not the single most important health problem of children, but work to provide children with better access to appropriate medicines is essential for achievement of the child health goals set. Taking into consideration the global aspect in the development of paediatric medicines the benefits of the regional paediatric initiatives can be spread worldwide. This chapter provides insights in the challenges and opportunities of developing paediatric medicines for health needs of children in the developing world. The Essential Medicines List for children first made available in 2008 serves as an example of the many tools available from WHO to improve children's access to the medicines they need.
每年约有900万儿童在5岁前死亡,其病症大多可用现有药物治愈。药品短缺并非儿童最重要的单一健康问题,但努力让儿童更好地获得适当药品对于实现既定的儿童健康目标至关重要。考虑到儿科药物开发的全球层面,区域儿科倡议的益处可在全球传播。本章深入探讨了为发展中世界儿童的健康需求开发儿科药物所面临的挑战和机遇。2008年首次推出的儿童基本药物清单就是世卫组织提供的众多工具之一,有助于改善儿童获得所需药物的机会。