Institute of Diabetes for Older People (IDOP), University of Bedfordshire, Luton, UK.
Diabet Med. 2011 Dec;28(12):1537-40. doi: 10.1111/j.1464-5491.2011.03421.x.
To analyse adverse drug events in older people with diabetes in the care home setting via incident reports obtained from the National Reporting and Learning Service.
A Freedom of Information request was made to the National Reporting and Learning Service via the National Patient Safety Agency. Within the National Reporting and Learning Service, reports on diabetes within the category of 'medication' using the location limiter of 'hospice or nursing home or residential home' were searched. We requested information about the number and nature of adverse drug event reports that had been received in relation to diabetes. The data were subdivided into reports (1) relating to insulin therapy and (2) oral glucose-lowering agents.
Data were collected between 1 January 2005 and 31 December 2009. There were 684 reports related to insulin and 84 incidents related to oral glucose-lowering agents. The most common error category with both types of drug therapy was wrong or unclear dose: 173 reports for insulin, including one death, and 20 reports for oral therapy.
Residents with diabetes in care homes are potentially at risk of harm from adverse drug events pertaining to insulin and oral glucose-lowering agents. Because of under-reporting, our data most likely represent only a fraction of events.
通过国家报告和学习服务机构从全国范围内获得的不良事件报告，分析疗养院环境中患有糖尿病的老年人的不良药物事件。
通过国家患者安全机构向国家报告和学习服务机构提出信息自由请求。在国家报告和学习服务机构内，使用“收容所或疗养院或养老院”的位置限制器，在“药物”类别中搜索关于糖尿病的报告。我们请求了有关与糖尿病相关的不良药物事件报告的数量和性质的信息。数据分为与胰岛素治疗相关的报告（1）和与口服降血糖药相关的报告（2）。
数据收集时间为 2005 年 1 月 1 日至 2009 年 12 月 31 日。与胰岛素相关的报告有 684 份，与口服降血糖药相关的事件有 84 份。两种药物治疗的最常见错误类别是剂量错误或不明确：胰岛素报告 173 份，包括 1 例死亡，口服治疗报告 20 份。
疗养院中患有糖尿病的居民可能面临与胰岛素和口服降血糖药相关的不良药物事件造成的伤害风险。由于报告不足，我们的数据很可能只代表了事件的一部分。
