University College Hospital NHS Trust, London, UK.
Acta Paediatr. 2012 Feb;101(2):128-31. doi: 10.1111/j.1651-2227.2011.02447.x. Epub 2011 Sep 23.
To investigate how clinically well, term newborns at risk of early-onset Group B streptococcal (EOGBS) disease are currently managed in the United Kingdom (UK).
Review of guidelines of UK neonatal units.
One hundred and twenty-five guidelines covering 157 neonatal units were received (71% of UK units), three of which were excluded from the review. We found great variation in every aspect for the management of EOGBS disease risk including the following: definition of risk factors; management of at-risk newborns; choice of antibiotics.
Our findings highlight the need for national consensus guidelines and clinical trials into the management of risk babies at risk of EOGBS disease.
调查目前英国(英国)如何对患有早发性 B 组链球菌(EOGBS)疾病风险的足月新生儿进行临床管理。
审查英国新生儿单位的指南。
共收到 125 条涵盖 157 个新生儿单位的指南(占英国单位的 71%),其中有 3 条被排除在审查范围之外。我们发现,在管理 EOGBS 疾病风险的各个方面都存在很大差异,包括以下内容:危险因素的定义;高危新生儿的管理;抗生素的选择。
我们的研究结果表明,需要制定国家共识指南,并进行临床试验,以管理患有 EOGBS 疾病风险的高危婴儿。