Centre National de Référence des Streptocoques (CNR-Strep), Groupe Hospitalier Cochin-Hôtel Dieu-Broca Assistance Publique Hôpitaux de Paris, Paris, France.
Clin Microbiol Infect. 2011 Oct;17(10):1587-9. doi: 10.1111/j.1469-0691.2011.03628.x. Epub 2011 Aug 29.
Group B streptococcus (GBS) has emerged as an important cause of invasive infection in adults. Here, we report the clinical and microbiological characteristics of 401 non-redundant GBS strains causing adult invasive infections collected during a 4-year period (2007-2010). Bacteraemia without focus (43.4%) and bone and joint infections (18.7%) were the main clinical manifestations. The distribution of capsular polysaccharide (CPS) type showed that types Ia, III, and V accounted for 71.8% of all strains. Resistance to erythromycin increased from 20.2% in 2007 to 35.3% in 2010, and was mainly associated with CPS type V harbouring the erm(B) resistant determinant.
B 群链球菌（GBS）已成为成人侵袭性感染的重要病因。在这里，我们报告了在 4 年期间（2007-2010 年）收集的 401 株非冗余导致成人侵袭性感染的 GBS 菌株的临床和微生物学特征。菌血症无病灶（43.4%）和骨和关节感染（18.7%）是主要的临床表现。荚膜多糖（CPS）型的分布表明，所有菌株中 71.8%为 Ia、III 和 V 型。对红霉素的耐药性从 2007 年的 20.2%增加到 2010 年的 35.3%，主要与携带 erm(B)耐药决定簇的 V 型 CPS 有关。
