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Severe calcification of the aorta (porcelain aorta) associated with sarcoidosis in a pediatric heart transplant recipient.

作者信息

Das Bibhuti B, Shoemaker Lawrence, Kim Edward, Mascio Christopher E, Austin Erle H

机构信息

Division of Pediatric Cardiology, Department of Pediatrics, University of Louisville School of Medicine, Louisville, KY, USA.

出版信息

Pediatr Transplant. 2012 Aug;16(5):E162-6. doi: 10.1111/j.1399-3046.2011.01557.x. Epub 2011 Aug 23.

DOI:10.1111/j.1399-3046.2011.01557.x
PMID:21883745
Abstract

We report a unique case of severe calcification of the aorta, bilateral coronary ostial stenoses and calcification of the mitral valve and left ventricle due to sarcoidosis. The patient underwent neonatal orthotopic heart transplantation secondary to hypoplastic left heart syndrome and developed hypercalcemia with other features of sarcoidosis at 10 yr of age. The mechanism for severe extra-renal calcification localized to the allograft is poorly understood, but may involve discordant local immune modulation and/or calcification-regulation between graft and host tissues.

摘要

相似文献

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Sarcoidosis as a cause of unappreciated hypercalcaemia in a patient with end-stage renal disease on peritoneal dialysis.结节病作为终末期肾病腹膜透析患者未被重视的高钙血症的病因。
BMJ Case Rep. 2013 Aug 1;2013:bcr2013010017. doi: 10.1136/bcr-2013-010017.