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结节病作为终末期肾病腹膜透析患者未被重视的高钙血症的病因。

Sarcoidosis as a cause of unappreciated hypercalcaemia in a patient with end-stage renal disease on peritoneal dialysis.

作者信息

Kwon Ami, Koh Eun Sil, Chung Sungjin, Kim Yong Kyun

机构信息

Department of Internal Medicine, The Catholic University of Korea Yeouido St. Mary's Hospital, Seoul, Republic of Korea.

出版信息

BMJ Case Rep. 2013 Aug 1;2013:bcr2013010017. doi: 10.1136/bcr-2013-010017.

DOI:10.1136/bcr-2013-010017
PMID:23907968
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3761446/
Abstract

The differential diagnosis of hypercalcaemia in patients with end-stage renal disease undergoing dialysis should be considered for causes related or unrelated to renal failure itself or therapies for renal failure. In particular, peritoneal dialysis may hinder awareness of a clinical problem due to its own peculiarities and effects on homeostasis of the body, thus creating misconceptions in interpreting laboratory data and diagnosing a disease. We describe here a case of systemic sarcoidosis which was delayed due to failure to recognise underestimated hypercalcaemia in a patient undergoing peritoneal dialysis. Clinicians need to remain aware of the change of minerals that may arise from peritoneal dialysis and should perform an extensive investigation for the cause of hypercalcaemia.

摘要

对于正在接受透析的终末期肾病患者,高钙血症的鉴别诊断应考虑与肾衰竭本身或肾衰竭治疗相关或不相关的病因。特别是腹膜透析,由于其自身特点以及对机体稳态的影响,可能会妨碍对临床问题的认识,从而在解读实验室数据和诊断疾病时产生误解。我们在此描述一例系统性结节病病例,该病例因未识别出接受腹膜透析患者中被低估的高钙血症而被延误诊断。临床医生需要留意腹膜透析可能引起的矿物质变化,并应对高钙血症的病因进行全面调查。

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本文引用的文献

1
Functional imaging in extrapulmonary sarcoidosis: FDG-PET/CT and MR features.肺外结节病的功能影像学:FDG-PET/CT 和 MR 特征。
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Tumoral calcinosis associated with hypercalcemia in a patient with chronic renal failure.肿瘤性钙质沉着症伴发于慢性肾衰竭患者的高钙血症。
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Plasma volume, albumin, and fluid status in peritoneal dialysis patients.腹膜透析患者的血浆容量、白蛋白和液体状况。
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Sarcoidosis-related hypercalcemia in 3 chronic hemodialysis patients.3例慢性血液透析患者的结节病相关高钙血症
Clin Nephrol. 2006 Jun;65(6):449-52. doi: 10.5414/cnp65449.
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Albumin-corrected or ionized calcium in renal failure? What to measure?肾衰竭时白蛋白校正钙还是离子钙?该测哪一个?
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