Sørensen Anne Grønborg, Barnung Steen, Rasmussen Lars Simon
Anæstesiafdelingen, Køge Sygehus, Denmark.
Ugeskr Laeger. 2011 Aug 29;173(35):2123-6.
Ketamine is a unique anaesthetic because it has both hypnotic and analgesic effects and also potential hallucinogenic side effects. Lack of cardiopulmonary depression makes the drug a popular choice for anaesthesia in the prehospital setting. In recent years ketamine has been found to have anti-hyperalgesic and opioid saving effects, opening to new ways of managing post-operative and chronic pain states. Recreational use of ketamine among night clubbers is increasing and makes acute and chronic symptoms of ketamine abuse a new challenge in emergency departments.
氯胺酮是一种独特的麻醉剂，因为它兼具催眠和镇痛作用，同时还存在潜在的致幻副作用。缺乏心肺抑制作用使得该药物成为院前麻醉的常用选择。近年来，人们发现氯胺酮具有抗痛觉过敏和节省阿片类药物的作用，为术后和慢性疼痛状态的管理开辟了新途径。夜店常客对氯胺酮的娱乐性使用日益增加，使得氯胺酮滥用的急性和慢性症状成为急诊科面临的新挑战。
