基础突触传递：星形胶质细胞说了算！
Basal synaptic transmission: astrocytes rule!
机构信息
Instituto Cajal, Consejo Superior de Investigaciones Científicas, Madrid 28002, Spain.
出版信息
Cell. 2011 Sep 2;146(5):675-7. doi: 10.1016/j.cell.2011.08.006.
PMID:21884929
Abstract
In this issue, Panatier et al. (2011) show that astrocytes detect synaptic activity induced by single action potentials and upregulate basal synaptic transmission through calcium-dependent mechanisms and purinergic signaling. These results demonstrate the relevance of astrocyte calcium in neurophysiology and confirm that astrocytes are actively involved in synaptic function.
摘要
在本期中，Panatier 等人（2011 年）表明，星形胶质细胞可以检测到由单个动作电位引起的突触活动，并通过钙依赖性机制和嘌呤能信号转导来增强基础突触传递。这些结果证明了星形胶质细胞钙在神经生理学中的相关性，并证实了星形胶质细胞积极参与突触功能。
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