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[未被怀疑的内脏利什曼病浸润鳞状细胞癌]

[Unsuspected visceral leishmaniasis infiltrating a squamous cell carcinoma].

作者信息

Armengot-Carbó M, Carmena-Ramón R, Rodrigo-Nicolás B, Ferrando-Marco J

机构信息

Servicio de Dermatología, Hospital Arnau de Vilanova, Valencia, España.

出版信息

Actas Dermosifiliogr. 2012 May;103(4):321-3. doi: 10.1016/j.ad.2011.04.016. Epub 2011 Aug 31.

Abstract

Amastigotes of the genus Leishmania have been observed in biopsies of apparently unrelated lesions in patients with AIDS and visceral leishmaniasis. We describe the case of a 40-year-old man with human immunodeficiency virus infection and severe immunodepression in whom the presence of the parasite was detected as an incidental finding on histological study of a perianal squamous cell carcinoma. This finding led to the diagnosis and subsequent treatment of previously unsuspected visceral leishmaniasis. In a review of the literature we have found no previous examples of this association.

摘要

在艾滋病和内脏利什曼病患者看似不相关的病变活检中,已观察到利什曼原虫属的无鞭毛体。我们描述了一名40岁人类免疫缺陷病毒感染且严重免疫抑制的男性病例,在对肛周鳞状细胞癌进行组织学研究时,偶然发现了该寄生虫的存在。这一发现导致了对先前未被怀疑的内脏利什曼病的诊断及后续治疗。在文献回顾中,我们未发现此前有这种关联的例子。

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