Botella Estrada R, Sanmartín Jiménez O, Febrer Bosch M I, Aliaga Boniche A, Salavert Lleti M, Roig Rico P, Nieto García A, Navarro Ibañez V
Servicio de Dermatología, Hospital General, Valencia.
Med Cutan Ibero Lat Am. 1990;18(2):119-23.
A HIV infected patient was admitted to hospital with fever diarrhoea and a cutaneous nodule on his left groin. Histopathological exam was diagnostic of cutaneous leishmaniasis. Subsequent exams disclosed Visceral Leishmaniasis. Three cycles of treatment (antimonials, pentamidine and metronidazole) were required for the clearance of lesions. The relation between immunosuppression and leishmania infection is commented and its role as an opportunistic pathogen is suggested. In these patients the infection takes a more aggressive course and has a worse response to the classic treatment with antimonials. These facts have made necessary the introduction of other alternative drugs.
一名艾滋病毒感染患者因发热、腹泻和左腹股沟处的皮肤结节入院。组织病理学检查诊断为皮肤利什曼病。随后的检查发现了内脏利什曼病。清除病变需要三个疗程的治疗（使用锑剂、喷他脒和甲硝唑）。文中讨论了免疫抑制与利什曼原虫感染之间的关系，并提示了其作为机会性病原体的作用。在这些患者中，感染病程更具侵袭性，对经典的锑剂治疗反应较差。这些事实使得引入其他替代药物成为必要。
