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转化生长因子β1 T868C 基因多态性与日本 2 型糖尿病患者脑梗死有关。

Transforming growth factor β1 T868C gene polymorphism is associated with cerebral infarction in Japanese patients with type 2 diabetes.

机构信息

Department of Metabolic Medicine, Osaka University Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka 565-0871, Japan.

出版信息

Diabetes Res Clin Pract. 2011 Dec;94(3):e57-60. doi: 10.1016/j.diabres.2011.08.005. Epub 2011 Aug 31.

DOI:10.1016/j.diabres.2011.08.005
PMID:21885147
Abstract

It is likely that the C allele of the polymorphism at position 29 of the translated sequence of transforming growth factor (TGF)-β1 gene, which codes a pleiotropic cytokine expressed in a variety of cells, is a susceptibility allele for cerebral infarction in Japanese type 2 diabetic patients.

摘要

该位置 29 翻译序列转化生长因子 (TGF)-β1 基因多态性的 C 等位基因可能是编码在各种细胞中表达的多功能细胞因子的等位基因，是日本 2 型糖尿病患者脑梗死的易感等位基因。

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