Rheumazentrum Ruhrgebiet, Landgrafenstr. 15, 44652 Herne, Germany.
J Rheumatol. 2011 Sep;38(9):2051-4. doi: 10.3899/jrheum.110423.
The ASAS/OMERACT MRI group recently described and defined magnetic resonance imaging (MRI) findings in sacroiliac joints (SIJ) that are essential for the diagnosis of sacroiliitis in patients with axial spondyloarthritis, including ankylosing spondylitis (AS). At the Outcome Measures in Rheumatology Clinical Trials (OMERACT) 2010 meeting, a special interest group (SIG) was formed to design a research agenda for the definition and description of structural lesions in the SIJ and the spine in patients with established AS. During the SIG, a summary of the previous work of the group was presented to all participants, containing: (1) a description of the current definitions of structural SIJ changes; (2) available scoring methods for SIJ changes; (3) data from a previous pilot MRI exercise on chronic SIJ changes performed by members of the group; and (4) a proposal for a research agenda for OMERACT 11. The group agreed on the project's scientific merits and the need to evaluate all available scoring methods and to have clear definitions for all possible abnormalities that can be seen on MRI, prior to the start of the exercise. It was also agreed that the exercise should include scoring of both structural and inflammatory lesions, due to lack of agreement about the best scoring method for assessing both types of lesions in AS. Participants agreed that longitudinal MRI over a certain period are needed to learn about the time sequence of pathologic changes and to understand the course of the disease. Finally, participants asked the group to add the development of a scoring method for structural changes in the spine in a subsequent exercise. Further to these objectives, all experts who agreed to contribute in the exercise will collaborate to achieve consensus on definitions and to organize training in the different scoring systems prior to the start of the project, with the aim to finalize the multiple reader exercise by the end of 2011, in time for OMERACT 11.
ASAS/OMERACT MRI 小组最近描述并定义了磁共振成像（MRI）在骶髂关节（SIJ）中的发现，这些发现对于诊断强直性脊柱炎患者的骶髂关节炎至关重要，包括强直性脊柱炎（AS）。在风湿病临床研究结局测量（OMERACT）2010 年会议上，成立了一个特别兴趣小组（SIG），旨在制定一个研究议程，用于定义和描述已确诊 AS 患者的 SIJ 和脊柱的结构病变。在 SIG 会议期间，向所有参与者介绍了该小组之前的工作摘要，其中包括：（1）描述当前结构 SIJ 变化的定义；（2）SIJ 变化的现有评分方法；（3）该小组成员之前进行的慢性 SIJ 变化试点 MRI 研究的数据；（4）OMERACT 11 的研究议程提案。该小组一致认为该项目具有科学价值，并且需要在开始之前评估所有可用的评分方法，并为 MRI 上可能出现的所有异常情况提供明确的定义。由于缺乏评估 AS 中这两种病变的最佳评分方法的共识，因此还一致认为该研究应包括结构和炎症病变的评分。参与者一致认为，需要进行一定时间的纵向 MRI 检查，以了解病理变化的时间顺序，并了解疾病的进程。最后，参与者要求小组在随后的研究中添加脊柱结构变化评分方法的开发。除了这些目标外，所有同意参与该研究的专家将合作达成定义共识，并在项目开始前组织不同评分系统的培训，目的是在 2011 年底之前完成多读者研究，以便及时提交给 OMERACT 11。
