Zochling Jane, Baraliakos Xenofon, Hermann Kay-Geert, Braun Jürgen
Menzies Research Institute, Private Bag 23, Hobart 7000, Australia.
Curr Opin Rheumatol. 2007 Jul;19(4):346-52. doi: 10.1097/BOR.0b013e32816a938c.
The past 18 months has seen considerable advances in the use of MRI for assessment of ankylosing spondylitis, to quantify active inflammation in the spine and sacroiliac joints which may not otherwise be detectable and to therefore measure change due to therapeutic interventions.
Characterization of the extension and morphology of inflammation in ankylosing spondylitis is now possible with MRI techniques. A number of randomized controlled trials of anti-tumour necrosis factor agents in ankylosing spondylitis have now been published showing regression of inflammatory lesions in the spine by MRI. Furthermore, the role of MRI for the early diagnosis of spondyloarthritis has become clearer. This review discusses the techniques used, the capabilities and the shortcomings of MRI in assessing ankylosing spondylitis patients.
MRI techniques have implications for early identification and intervention in patients with ankylosing spondylitis.
在过去18个月里,磁共振成像(MRI)在强直性脊柱炎评估中的应用取得了显著进展,可用于量化脊柱和骶髂关节的活动性炎症,这些炎症可能无法通过其他方式检测到,从而能够测量治疗干预导致的变化。
现在可以通过MRI技术对强直性脊柱炎炎症的范围和形态进行表征。目前已发表了多项关于抗肿瘤坏死因子药物治疗强直性脊柱炎的随机对照试验,结果显示通过MRI可观察到脊柱炎症性病变的消退。此外,MRI在脊柱关节炎早期诊断中的作用也变得更加明确。本综述讨论了在评估强直性脊柱炎患者时所使用的MRI技术、其功能及不足之处。
MRI技术对强直性脊柱炎患者的早期识别和干预具有重要意义。