阿米氟沙星与甲氧苄啶-磺胺甲恶唑治疗急性单纯性尿路感染10天疗程的随机对照试验。阿米氟沙星多中心试验组。
Randomized, controlled trial of a 10-day course of amifloxacin versus trimethoprim-sulfamethoxazole in the treatment of acute, uncomplicated urinary tract infection. Amifloxacin Multi-Center Trial Group.
作者信息
Boyko E J, Iravani A, Silverman M H, Schelling D J, Wright R A
机构信息
University of Colorado Health Science Center, Denver 80262.
出版信息
Antimicrob Agents Chemother. 1990 Apr;34(4):665-7. doi: 10.1128/AAC.34.4.665.
Abstract
We conducted a randomized controlled trial of orally administered amifloxacin versus trimethoprimsulfamethoxazole (TMP-SMX) as treatments of acute uncomplicated urinary tract infection in women. Amifloxacin at a dosage of 200 mg twice a day appeared as safe and effective as TMP-SMX, but amifloxacin at 400 mg twice a day tended to cause adverse events more frequently than did TMP-SMX.
摘要
我们进行了一项随机对照试验，比较口服阿米氟沙星与甲氧苄啶磺胺甲恶唑（TMP-SMX）治疗女性急性单纯性尿路感染的效果。每日两次服用200毫克的阿米氟沙星与TMP-SMX的安全性和有效性相当，但每日两次服用400毫克的阿米氟沙星比TMP-SMX更易引发不良事件。
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