一名儿童骨髓增生异常综合征转化为急性淋巴细胞白血病。
Transformation of myelodysplastic syndrome to acute lymphoblastic leukemia in a child.
作者信息
Gupta Vineeta, Bhatia Baldev
机构信息
Department of Pediatrics, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221005 India.
出版信息
Indian J Hematol Blood Transfus. 2010 Sep;26(3):111-3. doi: 10.1007/s12288-010-0015-5. Epub 2010 Oct 13.
Abstract
Childhood myelodysplastic syndrome (MDS) is an uncommon condition. Unlike adult MDS, pediatric patients have a more progressive course and rapidly transform to acute myeloid leukemia. Evolution to acute lymphoblastic leukemia is extremely rare. We report a 5 year old female child who presented with refractory anemia with excess blasts and transformed into acute lymphoblastic leukemia 4 months after initial diagnosis.
摘要
儿童骨髓增生异常综合征（MDS）是一种罕见的病症。与成人MDS不同，儿科患者的病程更具进展性，且会迅速转化为急性髓系白血病。转化为急性淋巴细胞白血病极为罕见。我们报告了一名5岁女童，她最初表现为伴有过多原始细胞的难治性贫血，并在初次诊断4个月后转化为急性淋巴细胞白血病。
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