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同一血管中晚期裸金属支架血栓形成伴药物洗脱支架通畅：一个提示性假说的实例

Very late bare metal stent thrombosis with concomitant patent drug eluting stent in the same vessel: a case for a suggestive hypothesis.

作者信息

Tanzilli Gaetano, Arrivi Alessio, Sordi Martina, Pavaci Herribert, Placanica Attilio, Mangieri Enrico

机构信息

Policlinico Umberto I, Viale del Policlinico 155, Roma, 00161, Italy.

出版信息

BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.06.2009.2014. Epub 2009 Sep 1.

DOI:10.1136/bcr.06.2009.2014
PMID:21886655
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3029616/
Abstract

We report a case of very late stent thrombosis of a bare metal stent with a concurrent drug eluting stent's patency in the same coronary vessel, in a patient undergoing primary angioplasty who discontinued his clopidogrel regimen a few weeks after successful deployment of the stents.

摘要

我们报告了一例在接受直接血管成形术的患者中，裸金属支架发生极晚期支架内血栓形成，而同一冠状动脉血管中的药物洗脱支架仍保持通畅的病例。该患者在支架成功植入几周后停用了氯吡格雷治疗方案。

相似文献

1
Very late bare metal stent thrombosis with concomitant patent drug eluting stent in the same vessel: a case for a suggestive hypothesis.同一血管中晚期裸金属支架血栓形成伴药物洗脱支架通畅：一个提示性假说的实例
BMJ Case Rep. 2009;2009. doi: 10.1136/bcr.06.2009.2014. Epub 2009 Sep 1.
2
Drug-eluting stent thrombosis 1,659 days after stent deployment: case report and literature review.药物洗脱支架置入1659天后发生支架内血栓形成：病例报告及文献综述
Tex Heart Inst J. 2010;37(3):343-6.
3
Sirolimus-eluting stents versus bare-metal stents in routine clinical use: a nonrandomized comparison.雷帕霉素洗脱支架与常规临床使用的裸金属支架：一项非随机对照研究。
Tex Heart Inst J. 2011;38(5):508-15.
4
Very late multivessel thrombosis of bare metal stents with concomitant patent drug-eluting stents after withdrawal of aspirin.
Int J Cardiol. 2008 Dec 17;131(1):e7-9. doi: 10.1016/j.ijcard.2007.06.144. Epub 2007 Sep 19.
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The conundrum of late and very late stent thrombosis following drug-eluting stent implantation.药物洗脱支架植入术后晚期及极晚期支架内血栓形成的难题。
Curr Opin Cardiol. 2007 Nov;22(6):565-71. doi: 10.1097/HCO.0b013e3282f02100.
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Value and limitations of target-vessel ischemia in predicting late clinical events after drug-eluting stent implantation.药物洗脱支架植入术后靶血管缺血在预测晚期临床事件中的价值与局限性
J Nucl Med. 2008 Apr;49(4):550-6. doi: 10.2967/jnumed.107.046771. Epub 2008 Mar 14.
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Outcomes with various drug eluting or bare metal stents in patients with diabetes mellitus: mixed treatment comparison analysis of 22,844 patient years of follow-up from randomised trials.在糖尿病患者中，不同药物洗脱支架或金属裸支架的结果：来自随机试验的 22844 患者年随访的混合治疗比较分析。
BMJ. 2012 Aug 10;345:e5170. doi: 10.1136/bmj.e5170.
8
Late clinical events after clopidogrel discontinuation may limit the benefit of drug-eluting stents: an observational study of drug-eluting versus bare-metal stents.停用氯吡格雷后的晚期临床事件可能会限制药物洗脱支架的益处：一项药物洗脱支架与裸金属支架的观察性研究
J Am Coll Cardiol. 2006 Dec 19;48(12):2584-91. doi: 10.1016/j.jacc.2006.10.026. Epub 2006 Nov 2.
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Post-operative simultaneous very late two-vessel drug eluting stent thrombosis with sparing of bare metal stent in a Jehovah's witness after clopidogrel withdrawal.一名耶和华见证会信徒停用氯吡格雷后，术后同时发生极晚期双支药物洗脱支架血栓形成，裸金属支架未受累。
J Cardiol Cases. 2013 Dec 13;9(2):57-60. doi: 10.1016/j.jccase.2013.10.004. eCollection 2014 Feb.
10
Comparison of a drug-eluting balloon first and then bare metal stent with a drug-eluting stent for treatment of de novo lesions: study protocol of a randomized controlled trial.药物洗脱球囊预处理后再行金属裸支架置入与药物洗脱支架置入治疗初发型病变的比较：一项随机对照试验的研究方案。
Trials. 2013 Feb 8;14:38. doi: 10.1186/1745-6215-14-38.

本文引用的文献

1
Stent thrombosis is not always stent thrombosis: de novo atherosclerosis in a stented coronary segment.支架内血栓并不总是支架内血栓：支架置入的冠状动脉段新发动脉粥样硬化。
Int J Cardiol. 2010 Sep 24;144(1):e19-21. doi: 10.1016/j.ijcard.2008.12.078. Epub 2009 Jan 21.
2
Drug-eluting stent implantation could be associated with long-term coronary endothelial dysfunction.药物洗脱支架植入可能与长期冠状动脉内皮功能障碍有关。
Int Heart J. 2007 Sep;48(5):553-67. doi: 10.1536/ihj.48.553.
3
The conundrum of late and very late stent thrombosis following drug-eluting stent implantation.药物洗脱支架植入术后晚期及极晚期支架内血栓形成的难题。
Curr Opin Cardiol. 2007 Nov;22(6):565-71. doi: 10.1097/HCO.0b013e3282f02100.
4
Drug-eluting stents and stent thrombosis: a cause for concern?药物洗脱支架与支架内血栓形成：值得担忧的原因？
Coron Artery Dis. 2006 Dec;17(8):661-5. doi: 10.1097/MCA.0b013e32801122b1.
5
Coronary stent thrombosis in the current drug-eluting stent era: insights from the ERACI III trial.当代药物洗脱支架时代的冠状动脉支架血栓形成：来自ERACI III试验的见解。
J Am Coll Cardiol. 2006 Jan 3;47(1):205-7. doi: 10.1016/j.jacc.2005.10.016. Epub 2005 Dec 9.
6
Indication of long-term endothelial dysfunction after sirolimus-eluting stent implantation.西罗莫司洗脱支架植入术后长期内皮功能障碍的指征。
Eur Heart J. 2006 Jan;27(2):166-70. doi: 10.1093/eurheartj/ehi571. Epub 2005 Oct 25.
7
Very late thrombosis after implantation of sirolimus eluting stent.西罗莫司洗脱支架植入术后极晚期血栓形成。
Heart. 2005 Jun;91(6):e45. doi: 10.1136/hrt.2004.056341.