毛发镜检查在遗传性毛干异常中的应用
Trichoscopy in genetic hair shaft abnormalities.
作者信息
Rakowska Adriana, Slowinska Monika, Kowalska-Oledzka Elzbieta, Rudnicka Lidia
机构信息
Department of Dermatology, CSK MSWiA, Warsaw, Poland.
出版信息
J Dermatol Case Rep. 2008 Jul 7;2(2):14-20. doi: 10.3315/jdcr.2008.1009.
BACKGROUND
Diagnosis of hair shaft abnormalities is based on light microscopic examination of more than 50 plucked hairs. The aim of this study was to verify whether hair shaft abnormalities may be visualized by trichoscopy (hair and scalp videodermoscopy) and to analyze trichoscopic features of common genetic hair shaft dysplasias.
METHOD
Patients with known genetic hair shaft disorders were included into the study. Trichoscopy was performed with the use of Fotofinder II videodermoscope. Images performed at 20-fold and 70-fold magnification were analysed. In selected cases 160-fold magnification was used for better visualization of hair shafts.
RESULTS
Our results show that characteristic light microscopy features of Netherton syndrome, monilethrix, woolly hair syndrome, pili torti, pili annulati and trichothiodystrophy may be visualized by trichoscopy.
CONCLUSION
Genetic hair shaft abnormalities may be diagnosed by trichoscopy in a single diagnostic session without the need of plucking or cutting them for diagnostic purposes.
背景
毛干异常的诊断基于对50多根拔下毛发的光学显微镜检查。本研究的目的是验证毛干异常是否可通过毛发镜检查（毛发和头皮视频皮肤镜检查）可视化，并分析常见遗传性毛干发育异常的毛发镜特征。
方法
已知遗传性毛干疾病的患者被纳入研究。使用Fotofinder II视频皮肤镜进行毛发镜检查。分析了20倍和70倍放大倍数下拍摄的图像。在选定病例中，使用160倍放大倍数以更好地观察毛干。
结果
我们的结果表明，Netherton综合征、念珠状发、羊毛状发综合征、扭曲发、环状发和毛发硫营养不良的特征性光学显微镜特征可通过毛发镜检查可视化。
结论
遗传性毛干异常可通过毛发镜检查在单次诊断过程中进行诊断，无需为诊断目的而拔取或剪下毛发。
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