Cozzani Emanuele, Scaparro Manuela, Parodi Aurora
Di.S.E.M. Section of Dermatology, University of Genoa, Italy.
J Dermatol Case Rep. 2009 Dec 30;3(4):60-1. doi: 10.3315/jdcr.2009.1037.
Statins are known to have a number of cutaneous adverse effects including the induction of autoimmune diseases like systemic and subacute lupus erythematosus, dermatomyositis, polymyositis, lichen planus pemphigoides and the drug reaction with eosinophilia and systemic symptoms (DRESS). Statins have been also reported as a triggering factor of psoriasis. We report a case of psoriasis vulgaris that worsened three months after atorvastatin was introduced and improved after its discontinuance.
已知他汀类药物有多种皮肤不良反应，包括诱发自身免疫性疾病，如系统性和亚急性红斑狼疮、皮肌炎、多发性肌炎、扁平苔藓类天疱疮以及药物超敏反应伴嗜酸性粒细胞增多和全身症状（DRESS）。也有报道称他汀类药物是银屑病的诱发因素。我们报告一例寻常型银屑病病例，在开始服用阿托伐他汀三个月后病情加重，停药后病情改善。
