Lopes Márcio Ajudarte, Vargas Pablo Agustin, Almeida Oslei Paes, Takahama Ademar, León Jorge Esquiche
Department of Oral Pathology, School of Dentistry of Piracicaba/UNICAMP, Piracicaba, São Paulo, Brazil.
J Oral Maxillofac Pathol. 2009 Jul;13(2):67-9. doi: 10.4103/0973-029X.57672.
Traumatic neuromas are characterized by the presence of pain, burning, or paresthesia, associated with a history of trauma, normally surgery, in the same site. In the oral cavity, the most commonly affected sites are the lip, tongue, and mental nerve area. Pressure on the suspected area usually provokes pain. They microscopically consist of a proliferation of nerve fascicles embedded in a background of collagen. We present a case of a 42-year-old Latin American female patient complaining of a painful solitary nodule erupting on the lingual surface of the mandibular body. Histopathological analysis showed a traumatic neuroma associated with mature ganglion cells, which is an extremely unusual finding. After complete removal of the lesion the symptoms disappeared. To the best of our knowledge, this is the first case of a unique lesion with unusual clinical and histopathological features reported in the English language literature.
创伤性神经瘤的特征是存在疼痛、灼痛或感觉异常,且与同一部位的创伤史(通常为手术史)相关。在口腔中,最常受累的部位是嘴唇、舌头和颏神经区域。对疑似区域施压通常会引发疼痛。它们在显微镜下由嵌入胶原背景中的神经束增生组成。我们报告一例42岁拉丁裔女性患者,主诉在下颌体舌面出现一个疼痛性孤立结节。组织病理学分析显示为伴有成熟神经节细胞的创伤性神经瘤,这是一个极其罕见的发现。病变完全切除后症状消失。据我们所知,这是英文文献中报道的首例具有独特临床和组织病理学特征的独特病变。