犬舌神经节神经瘤

Lingual ganglioneuroma in a dog.

作者信息

Goto Minami, Yonemaru Kayoko, Hirata Akihiro, Furuhashi Hidenari, Yanai Tokuma, Sakai Hiroki

机构信息

Laboratory of Veterinary Pathology, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan.

Comparative Cancer Center Faculty of Applied Biological Sciences, Gifu University, 1-1 Yanagido, Gifu 501-1193, Japan.

出版信息

J Vet Med Sci. 2018 Mar 24;80(3):488-491. doi: 10.1292/jvms.17-0602. Epub 2018 Jan 25.

DOI:10.1292/jvms.17-0602

PMID:29367496

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5880831/

Abstract

A mass was found at the base of the dorsum linguae of a male 11-year-old Labrador retriever. The tumor comprised of ganglion cells and Schwannian cells with Verocay bodies. The ganglion cells were positive for neuron-specific enolase, S-100, nerve growth factor receptor, and beta III tubulin. The Schwannian cells were positive for neuron-specific enolase, S-100, nerve growth factor receptor, and glial fibrillary acidic protein. The lingual mass was diagnosed as a ganglioneuroma. To our knowledge, there has been no previous report of a lingual ganglioneuroma in a dog.

摘要

在一只11岁雄性拉布拉多猎犬的舌背根部发现一个肿块。该肿瘤由神经节细胞和具有Verocay小体的施万细胞组成。神经节细胞对神经元特异性烯醇化酶、S-100、神经生长因子受体和βⅢ微管蛋白呈阳性反应。施万细胞对神经元特异性烯醇化酶、S-100、神经生长因子受体和胶质纤维酸性蛋白呈阳性反应。该舌部肿块被诊断为神经节神经瘤。据我们所知，此前尚无犬舌部神经节神经瘤的报道。