2nd Surgery Department, General Hospital of Tripolis, Tripolis, Greece.
Tech Coloproctol. 2011 Oct;15 Suppl 1:S87-9. doi: 10.1007/s10151-011-0753-x.
The carcinomas of the anal canal consist of truly rare clinical entities compared to the most common colorectal malignancies. Consequently, little have been reported on their natural history and course.
The present study is aiming to describe the experience of our clinic with anal cancer and to clarify the incidence of the disease in the Hellenic population.
A 5-year retrospective study was conducted. We searched all cases of patients, diagnosed with anal carcinoma in our medical center. Medical records and histological examination results were all thoroughly registered and evaluated.
On the whole, 60 patients were diagnosed with a malignant tumor of anal canal. Among them, 25 cases involved anal adenocarcinoma, 26 cases referred to a squamous cell carcinoma and in 5 cases, Bowen disease was identified. Two melanomas, one GIST stromal tumor and one case of Paget disease, were recognized as well.
It seems that in our center the frequency and prevalence of anal adenocarcinoma is increased compared to the results from international data. More studies involving larger series of patients are required in order to shed further light in the true incidence of anal cancer and it subtypes in Hellenic population.
与最常见的结直肠恶性肿瘤相比，肛管癌属于真正罕见的临床实体。因此，关于其自然病史和病程的报道较少。
本研究旨在描述我们诊所对肛门癌的经验，并阐明该病在希腊人群中的发病率。
进行了一项为期 5 年的回顾性研究。我们搜索了在我们医疗中心诊断为肛管癌的所有患者的病例。所有病历和组织学检查结果均进行了详细的登记和评估。
总共诊断出 60 例肛门 canal 恶性肿瘤患者。其中，25 例为肛门腺癌，26 例为鳞状细胞癌，5 例为 Bowen 病。还发现了 2 例黑色素瘤、1 例 GIST 间质瘤和 1 例 Paget 病。
在我们中心，肛门腺癌的频率和患病率似乎高于国际数据。需要进行更多涉及更大系列患者的研究，以便进一步阐明希腊人群中肛门癌及其亚型的真实发病率。
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