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髋部骨折中骨密度和世卫组织骨折风险评估阈值的有效性。

Validity of bone mineral density and WHO fracture risk assessment thresholds in hip fractures.

机构信息

Department of Orthopedics, Imam Khomeini Hospital, Urmia University of Medical Sciences, Urmia, Iran.

出版信息

Arch Iran Med. 2011 Sep;14(5):352-4.

PMID:21888461
Abstract

Hip fractures are common and serious consequence of osteoporosis. Bone mineral density (BMD) measurement and the World Health Organization (WHO) fracture risk assessment tool are considered to predict the hip osteoporotic fractures. In this study, their sensitivities in hip fracture cases are evaluated. BMD and WHO probability of fracture risk were determined in 71 hip fractures ≥ 50 years of old. Totally, 65% of patients had ≤-2.5 BMD T score. 81% of patients had above the upper interventional threshold of WHO fracture risk probability model. Sensitivities were low in 50-59 year age group with progression in older age groups. Results of BMD T score and fracture risk probabilities were not significant between men and women. There were 23% and 49% sensitivities of less than or equal to -2.5 T score in the 50-59 and 60-69 year age groups with a 31% sensitivity of greater than 3% probability of hip fracture risk in the 50-59 year age group, both of which were not valid for predicting hip fracture risk.

摘要

髋部骨折是骨质疏松症的常见且严重后果。骨密度(BMD)测量和世界卫生组织(WHO)骨折风险评估工具被认为可用于预测髋部骨质疏松性骨折。本研究评估了它们在髋部骨折病例中的敏感性。对 71 例年龄≥50 岁的髋部骨折患者进行了 BMD 和 WHO 骨折风险概率的测定。总共,65%的患者的 BMD T 评分≤-2.5。81%的患者的 WHO 骨折风险概率模型的干预上限以上。在年龄较大的年龄组中,50-59 岁年龄组的敏感性较低,且随年龄增长而降低。BMD T 评分和骨折风险概率在男性和女性之间无显著差异。50-59 岁年龄组中,BMD T 评分≤-2.5 的敏感性为 23%和 49%,50-59 岁年龄组中髋部骨折风险概率大于 3%的敏感性为 31%,两者均不能有效预测髋部骨折风险。

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