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胃腺癌手术和辅助治疗。

Gastric adenocarcinoma surgery and adjuvant therapy.

机构信息

Division of Surgical Oncology, Department of Surgery, Winship Cancer Institute, Emory University, 1365C Clifton Road, Northeast 2nd Floor, Atlanta, GA 30322, USA.

出版信息

Surg Clin North Am. 2011 Oct;91(5):1039-77. doi: 10.1016/j.suc.2011.06.009.

DOI:10.1016/j.suc.2011.06.009
PMID:21889029
Abstract

Gastric adenocarcinoma is one of the most common causes of death worldwide. Surgical resection remains the mainstay of therapy, offering the only chance for complete cure. Resection is based on the principles of obtaining adequate margins, with the extent of lymphadenectomy remaining controversial. Neoadjuvant and adjuvant therapies are used to reduce local recurrence and improve long-term survival. This article reviews the literature and provides a summary of surgical management options and neoadjuvant/adjuvant therapies for gastric adenocarcinoma.

摘要

胃腺癌是全球最常见的死亡原因之一。手术切除仍然是主要的治疗方法,是唯一能够完全治愈的机会。切除的基础是获得足够的切缘,淋巴结清扫的范围仍存在争议。新辅助和辅助治疗用于减少局部复发并提高长期生存率。本文回顾了文献,总结了胃腺癌的手术治疗选择和新辅助/辅助治疗。

相似文献

1
Gastric adenocarcinoma surgery and adjuvant therapy.胃腺癌手术和辅助治疗。
Surg Clin North Am. 2011 Oct;91(5):1039-77. doi: 10.1016/j.suc.2011.06.009.
2
Adjuvant and neoadjuvant therapy for gastric cancer.胃癌的辅助治疗和新辅助治疗。
Surg Clin North Am. 2005 Oct;85(5):1033-51, viii. doi: 10.1016/j.suc.2005.05.004.
3
Perspectives in adjuvant therapy of gastric cancer.胃癌辅助治疗的观点。
Oncology. 2009;77 Suppl 1:38-42. doi: 10.1159/000258494. Epub 2010 Feb 2.
4
Treatment trends and predictors of adjuvant and neoadjuvant therapy for gastric adenocarcinoma in the United States.美国胃腺癌辅助和新辅助治疗的趋势和预测因素。
Ann Surg Oncol. 2013 Feb;20(2):362-70. doi: 10.1245/s10434-012-2552-7. Epub 2012 Aug 14.
5
[The value of adjuvant and neoadjuvant chemotherapy in treatment of stomach carcinoma].[辅助和新辅助化疗在胃癌治疗中的价值]
Wien Klin Wochenschr. 1996;108(16):496-504.
6
Combined modality therapy of gastric cancer.胃癌的综合治疗
Surg Oncol Clin N Am. 1997 Oct;6(4):741-7.
7
Preoperative radiochemotherapy in gastric cancer: another ongoing shift from adjuvant to neoadjuvant?胃癌术前放化疗:是否正在从辅助治疗向新辅助治疗转变?
J Clin Oncol. 2005 Jun 1;23(16):3870; author reply 3870-1. doi: 10.1200/JCO.2005.05.204.
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Morbidity, mortality, and pathological response in patients with gastric cancer preoperatively treated with chemotherapy or chemoradiotherapy.胃癌患者术前接受化疗或放化疗的发病率、死亡率和病理反应。
J Surg Oncol. 2011 Aug 1;104(2):124-9. doi: 10.1002/jso.21947. Epub 2011 Apr 20.
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Advances in the treatment of patients with gastric adenocarcinoma.胃腺癌患者治疗方面的进展。
Acta Oncol. 2007;46(3):277-85. doi: 10.1080/02841860701218634.
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Optimal management of resectable gastric adenocarcinoma.可切除胃腺癌的优化管理
Expert Rev Anticancer Ther. 2015;15(8):931-41. doi: 10.1586/14737140.2015.1054814. Epub 2015 Jul 11.

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A Comparative Analysis of Laparoscopic Gastrectomy Versus Laparoscopic-Assisted Gastrectomy: The Overall and Disease-Free Survival.腹腔镜胃切除术与腹腔镜辅助胃切除术的比较分析:总生存率和无病生存率
Cureus. 2024 Mar 22;16(3):e56730. doi: 10.7759/cureus.56730. eCollection 2024 Mar.
2
Impact of the Interval between Neoadjuvant Chemotherapy and Gastrectomy on Pathological Response and Survival Outcomes for Patients with Locally Advanced Gastric Cancer: A Meta-analysis.新辅助化疗与胃切除术间隔时间对局部进展期胃癌患者病理反应及生存结局的影响:一项Meta分析
Euroasian J Hepatogastroenterol. 2022 Jul-Dec;12(2):81-91. doi: 10.5005/jp-journals-10018-1382.
3
Regional and racial disparity in proximal gastric cancer survival outcomes 1996-2016: Results from SEER and China National Cancer Center database.
1996-2016 年近端胃癌生存结局的区域性和种族差异:来自 SEER 和中国国家癌症中心数据库的结果。
Cancer Med. 2021 Jul;10(14):4923-4938. doi: 10.1002/cam4.4033. Epub 2021 Jun 9.
4
Timing of surgery after neoadjuvant chemotherapy for gastric cancer: Impact on outcomes.新辅助化疗后胃癌手术时机:对结局的影响。
World J Gastroenterol. 2018 Jan 14;24(2):257-265. doi: 10.3748/wjg.v24.i2.257.
5
Microsatellite Alterations and Protein Expression of 5 Major Tumor Suppressor Genes in Gastric Adenocarcinomas.胃腺癌中5种主要肿瘤抑制基因的微卫星改变与蛋白表达
Transl Oncol. 2018 Feb;11(1):43-55. doi: 10.1016/j.tranon.2017.10.007. Epub 2017 Nov 21.
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Factors associated with early recurrence after curative surgery for gastric cancer.胃癌根治性手术后早期复发的相关因素。
World J Gastroenterol. 2015 May 21;21(19):5934-40. doi: 10.3748/wjg.v21.i19.5934.
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Racial and ethnic disparities in gastric cancer outcomes: more important than surgical technique?胃癌治疗结果中的种族和民族差异:比手术技术更重要吗?
World J Gastroenterol. 2014 Sep 7;20(33):11546-51. doi: 10.3748/wjg.v20.i33.11546.
8
Modified DCF (mDCF) regimen seems to be as effective as original DCF in advanced gastric cancer (AGC).改良 DCF(mDCF)方案似乎与原 DCF 方案在晚期胃癌(AGC)中的疗效相当。
Clin Transl Oncol. 2013 May;15(5):403-8. doi: 10.1007/s12094-012-0942-8. Epub 2012 Oct 2.