Merchant Shaila J, Li Lily, Kim Joseph
Shaila J Merchant, Lily Li, Joseph Kim, Division of Surgical Oncology, Department of Surgery, City of Hope National Medical Center, Duarte, CA 91010, United States.
World J Gastroenterol. 2014 Sep 7;20(33):11546-51. doi: 10.3748/wjg.v20.i33.11546.
Racial and ethnic disparities in cancer care are major public health concerns and their identification is necessary to develop interventions to eliminate these disparities. We and others have previously observed marked disparities in gastric cancer outcomes between Eastern and Western patients. These disparities have long been attributed to surgical technique and extent of lymphadenectomy. However, more recent evidence suggests that other factors such as tumor biology, environmental factors such as Helicobacter pylori infection and stage migration may also significantly contribute to these observed disparities. We review the literature surrounding disparities in gastric cancer and provide data pertaining to potential contributing factors.
癌症治疗中的种族和民族差异是主要的公共卫生问题，识别这些差异对于制定消除这些差异的干预措施至关重要。我们和其他人之前已经观察到东西方患者在胃癌治疗结果上存在显著差异。长期以来，这些差异一直归因于手术技术和淋巴结清扫范围。然而，最近的证据表明，其他因素，如肿瘤生物学、幽门螺杆菌感染等环境因素以及分期迁移，也可能对这些观察到的差异有显著影响。我们回顾了有关胃癌差异的文献，并提供了与潜在促成因素相关的数据。
