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儿童食管狭窄的内镜下球囊扩张术

Endoscopic balloon dilatation of esophageal strictures in children.

作者信息

Alshammari J, Quesnel S, Pierrot S, Couloigner V

机构信息

Pediatric ENT Department, Service d'ORL Pédiatrique, Hôpital Necker - Enfants Malades, AP-HP, University of Paris V, 149, rue de Sèvres, 75015 Paris, France.

出版信息

Int J Pediatr Otorhinolaryngol. 2011 Nov;75(11):1376-9. doi: 10.1016/j.ijporl.2011.07.031. Epub 2011 Sep 1.

Abstract

AIM OF THE STUDY

To assess the efficacy and safety of endoscopic balloon dilatation of esophageal strictures in children.

DESIGN

retrospective case series; population: 49 patients under 18 years of age referred to our center for esophageal strictures; treatment: endoscopic balloon dilatation; outcome parameters: residual dysphagia, weight gain, iatrogenic esophageal perforation, assessment of the esophageal lumen by endoscopy or esophagogram.

RESULTS

The three main etiologies were esophageal atresia (49%; n=24), corrosive injury (25%; n=12), and epidermolysis bullosa (14%; n=7), followed by a heterogeneous group of rarer causes (12%; n=6). The number of dilatations ranged from 1 to 8 sessions per patient (median ± SEM: 2 ± 0.3). The length of the follow-up period ranged from 20 to 109 months (median ± SEM: 40 ± 4 months). Treatment was successful in 86% of cases (n=42). Twelve percent of patients (n=6) had a residual stenosis requiring surgery, and a further one still experienced swallowing difficulties requiring enteral nutrition via gastrostomy in spite of the absence of significant residual stricture. Results were less satisfactory in cases of corrosive injury than with other etiologies. Three esophageal perforations were observed (6% of patients; 2% of procedures). All were medically treated.

CONCLUSIONS

Endoscopic balloon dilatation is a simple, safe and efficacious treatment of esophageal strictures in children.

摘要

研究目的

评估儿童食管狭窄内镜下球囊扩张术的疗效和安全性。

设计

回顾性病例系列研究;研究对象:49例18岁以下因食管狭窄转诊至本中心的患者;治疗方法:内镜下球囊扩张术;观察指标:残余吞咽困难、体重增加、医源性食管穿孔、通过内镜或食管造影评估食管腔。

结果

三种主要病因是食管闭锁(49%;n = 24)、腐蚀性损伤(25%;n = 12)和大疱性表皮松解症(14%;n = 7),其次是一组病因各异的罕见病因(12%;n = 6)。每位患者的扩张次数为1至8次(中位数±标准误:2±0.3)。随访期为20至109个月(中位数±标准误:40±4个月)。86%的病例(n = 42)治疗成功。12%的患者(n = 6)有残余狭窄需要手术治疗,另有1例尽管没有明显的残余狭窄,但仍有吞咽困难,需要通过胃造口进行肠内营养。腐蚀性损伤病例的结果不如其他病因的病例令人满意。观察到3例食管穿孔(占患者的6%;占操作的2%)。所有穿孔均经内科治疗。

结论

内镜下球囊扩张术是治疗儿童食管狭窄的一种简单、安全且有效的方法。

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