Epilepsy Center, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.
Epilepsy Behav. 2011 Oct;22(2):404-6. doi: 10.1016/j.yebeh.2011.07.019. Epub 2011 Sep 1.
Ictal singing has been rarely reported and the neural networks underlying this specific symptom remain unknown. We report a nineteen-year-old man with medically refractory seizures who exhibited ictal singing and laughing. He underwent intracranial stereotactic EEG recording which demonstrated ictal activity in medial and dorsolateral regions of the left frontal lobe in the generation of ictal singing. Thereafter, a left frontal resection of the superior and middle frontal gyri made him seizure-free. Among the previously reported cases of ictal singing, the symptomatogenic zones included bilateral frontal and temporal lobes. The wide variance of ictal onset zones suggests that the mechanism of ictal singing is probably related to the recruitment of music-related neural networks in different regions of both hemispheres rather than activation of a specific cortical region.
发作性歌唱很少见，其潜在的神经网络尚不清楚。我们报告了一例 19 岁男性，药物难治性癫痫发作，表现为发作性歌唱和大笑。他接受了颅内立体脑电图记录，显示左侧额中侧和背外侧区域的发作性活动导致发作性歌唱。此后，左额前上和中回切除使他无癫痫发作。在之前报道的发作性歌唱病例中，症状发生区包括双侧额叶和颞叶。发作起始区的广泛差异表明，发作性歌唱的机制可能与半球不同区域与音乐相关的神经网络的募集有关，而不是特定皮质区域的激活。
